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Diabetes Discussion
Type 1 Diabetes
Which is worse? - 1hr at 8mmol or 10min at 15
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<blockquote data-quote="SamJB" data-source="post: 1081703" data-attributes="member: 45322"><p>Hi Westley,</p><p>I work in pharma, where we need to calculate the exposure someone has had to something (e.g. a drug). What does the damage in diabetics is exposure to glucose. We calculate exposure by looking at a line graph of time on the x-axis and concentration on the y-axis. The exposure is calcualted by the area that is under the line. </p><p></p><p>We can easily calculate the exposure to glucose in the examples you gave:</p><p></p><p>Exposure = time x concentration</p><p></p><p>For 60 mins at 8 mmols/l:</p><p></p><p>60 x 8 = 480</p><p></p><p>For 10 mins at 15 mmols/l:</p><p></p><p>10 x 15 = 150</p><p></p><p>So, you're more exposed to glucose when you spend an hour at 8 mmol/l. However, there are three points to make: is 8 a safe level? Will you only ever be 10 mins at 15? What is an unsafe exposure?</p></blockquote><p></p>
[QUOTE="SamJB, post: 1081703, member: 45322"] Hi Westley, I work in pharma, where we need to calculate the exposure someone has had to something (e.g. a drug). What does the damage in diabetics is exposure to glucose. We calculate exposure by looking at a line graph of time on the x-axis and concentration on the y-axis. The exposure is calcualted by the area that is under the line. We can easily calculate the exposure to glucose in the examples you gave: Exposure = time x concentration For 60 mins at 8 mmols/l: 60 x 8 = 480 For 10 mins at 15 mmols/l: 10 x 15 = 150 So, you're more exposed to glucose when you spend an hour at 8 mmol/l. However, there are three points to make: is 8 a safe level? Will you only ever be 10 mins at 15? What is an unsafe exposure? [/QUOTE]
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Type 1 Diabetes
Which is worse? - 1hr at 8mmol or 10min at 15
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