- Messages
- 337
- Type of diabetes
- Don't have diabetes
- Treatment type
- Diet only
- Dislikes
- ?
Hi
Any suggestions etc..
I have the “hunter” (“thrifty”) gene do you?
This is an explanation of why I had such disturbing symptoms for about 50 years until I figured out that a very low sugar/starch/alcohol(S) diet seemed to be relieving my symptoms. It then took approximately an additional 2 years for almost all my symptoms to clear. It then took about 6 years and a lot of serendipity to figure out what was the problem and that turned out to be only a start of a journey. I am sorry that this explanation is long but I have been told it is complicated.
It is a fact that about ½ the women in India have my gene and it leads to all the sugar problems in pregnancy. Considering my gene leads to a diagnosis of prediabetic that is what Indians told me. I quote from one nurse who said about the sugar problems in pregnancy “it must be genetic”.
Partially, because my informal interviews with a hand full of chubby Indian women are not backed up by information on Google.
I wish to help fund a study that follows the glucose tolerance tests (GTT, see footnotes 1 and 2) of women before, during and after pregnancy.
A major reason for this study is that a doctor on PBS in 2015 drew two graphs of a GTT. GTT’s run for 2 hours. The first GTT went up and then down. He indicated this is the expected GTT. The second GTT slowed its rate of assent but was still rising as he lifted his marker. The second is my GTT (2) taken in 1964. Does anyone know the name of this doctor? He defined such people as having a “hunter” gene. He said people with this GTT did not lose weight on his weight loss diet. The diabetic community says this sounds like the “thrifty” gene. Since people with the “hunter” gene should be better able to survive famines there must be a downside to this gene. I guess one downside is that women with this gene have problems controlling their blood sugar during pregnancy.
The following paragraph contains my actionable conclusions. Details describing them and what lead up to some of these conclusions follow.
Probably my most important conclusion is that Type 2 diabetes could be due to hormones used to create insulin resistance being produced all the time. Researchers where are you? Also:
In my wildest dreams this article would eventually lead to everyone getting a baseline glucose tolerance test (GTT); I strongly suggest you ask your physician to take a GTT to find out if you have the normal GTT or the “hunter” GTT.
Another dream is that doctors would publicize that you can get an autoimmune disease if you have the “hunter” gene. If you have the “hunter” gene and become chronically fatigued I suggest you see if cutting back your sugar/starch/alcohol (S) improves how you feel.
Judging from what people with reactive hypoglycemia post I have a dream that doctors will realize that what is necessary to avoid all the symptoms of either form of reactive hypoglycemia is to not let the blood sugar go above an unknown value. This value can be completely different for different people. I further guess that both types of reactive hypoglycemia are due to the same autoimmune problem. From my posts on diabetes.co.uk I conclude that the treatment for reactive hypoglycemia in the U.S. and U.K. are different. The difference comes down to, is the hunter gather diet good for humans? Do we need grains and significant fruits for a healthy diet? My personal experience indicates that a lot of small balanced meals is impractical. You are on the knife edge of going into reactive hypoglycemia.
An even bigger dream is that a very low sugar/starch/alcohol(S) diet would be tried on all type 2 diabetics and it successfully controlled high blood sugar; for some diabetics this may be a better option then the standard treatment. In that case make sure you monitor your blood sugar to see if you have cut your sugar/starch/alcohol (S) enough.
Another dream is that it would be found that people with the “hunter” gene tend to become fat on the modern diet; for me a low fat diet worked. If you have the “hunter” gene see if this works for you. As the weight loss doctor said, “people with the hunter gene do not lose weight on his weight loss diet”. This would then lead to the following obvious question. Is the hunter gene the reason for the weight problems, when they try the modern diet, with the Indian population, American Indians, Pacific Islanders etc.…? If so, all my advice follows for these people.
After years on a severe very low S diet my high blood pressure corrected itself without medication.
Is the amount of insulin produced by our diet the fundamental reason for most high blood pressure? Could a low S diet generally lead to a correction of high blood pressure?
I was interrupted by an Indian while I sprouted my theories by “½ the people of India are prediabetic (1), but they do not get diabetes”. This indicates why. I also present a theory about an alternate method of sugar storage used by some humans. I have the following question: assume a women has sugar problems during pregnancy. How can you see if her GTT has returned to normal after pregnancy if you don’t know what is her normal GTT? I have the following observation if women with the “hunter” gene are much more susceptible to sugar problems during pregnancy, maybe you can explore possible pre pregnancy interventions with these women.
In 1964 a doctor looked at my GTT and said I was prediabetic (1) and was developing insulin resistance. I am fat and have done all the wrong things, but I am not a diabetic. The reason for my GTT in 1964 is that I get low blood sugar many hours after eating too much (S). I know of 4 other people with the hunter gene who also have this symptom. We also have other symptoms starting with much lower values of (S). The symptoms are some significant degree of brain fog and fatigue. These symptoms are controlled by never letting our blood sugar go above some (unknown) value.
I theorize that the hunter gene allows people to only store sugar when their blood sugar rises above some value (3). Consider the following. Evolutionary changes are often additions to existing processes. Women with the “hunter” gene have insulin resistance in pregnancy. Insulin is needed to process protein. Look at my glucose tolerance test (2). I am led to the following weird conclusion. With the “hunter” gene people are normally in a state of insulin resistance. They are usually simulating type 2 diabetes. When their body determines that the blood sugar is heading for dangerous territory, that it will affect the general chemistry of the blood, the body cuts insulin resistance and if necessary produces insulin to keep the blood sugar from going too high. It waits over an hour in this mode and then produces enough insulin to mop up the excess sugar in the blood. My wild guess is that the “hunter” or “thrifty” gene people are constantly producing hormones to create insulin resistance (7). When the blood sugar gets too large, they stop producing these hormones and if necessary produce a little insulin, even though they are somewhat insulin resistant. After a time gap to allow the hormones to clear, they produce a large enough quantity of insulin to make most of the sugar in their blood become fat. Sometime into this insulin release they are supposed to restart the hormones. People with reactive hypoglycemia do not restart the hormones. I speculate that people with reactive hypoglycemia do not wait the necessary time if they do not have to produce insulin to prevent their blood sugar from rising too high. Their fatigue is due to not turning on the hormones which produce insulin resistance and ending up with mild low blood sugar for extended periods of time and/or trying to start the hormones. I further speculate that people with the “normal” sugar processing also use these hormones for a short time when hypoglycemia threatens. I think that people with either of the reactive hypoglycemia symptoms have disabled this response.
I am on a very low (S) diet. I am simulating a type 2 diabetic almost all the time. I speculate this was true for the hunters from which I arose.
I have reason to believe that I had an episode which was an autoimmune reaction (4). I therefore theorize that doctors should be aware that it is possible for people to have one type of cell of their adrenal glands destroyed. This compromises the possibly complicated chemistry that allows sugar to be stored based on their blood sugar in “hunter” gene people. Doctors should advise people with the reactive hypoglycemia and GTT that they will feel better if they carefully control the (S) in their diet (5). I only know of 5 people with the “hunter” gene autoimmune problem I describe and only two have had their symptoms diagnosed by doctors. The doctors noted that diet controlled their problem but had no idea what was happening. I therefore suggest that doctors make people with the hunter gene aware of this possibility.
My diet is low enough in (S) that with my hunter gene I have turned off the effects of insulin. My evidence is that my fasting blood sugar has risen, but it is very normal, because I never lower it with insulin (6). Further, on occasion, I have gained weight on this diet. I noticed that years ago I was able to lose about 80 pounds in approximately 1 year on a crash diet of pasta with cottage cheese with enough vegetables for vitamins. I also notice that I am presently losing weight on my very low (S) diet by cutting out almost all cheese. Since my meat portions are comparatively small, I assume I am losing weight for the standard reason. Further, I have no discernible problem with exercise even with my extreme diet with very low (S). My fasting blood sugar has stabilized at near the highest but normal values, ever (6). Have I returned to my hunter roots.
Any suggestions etc..
I have the “hunter” (“thrifty”) gene do you?
This is an explanation of why I had such disturbing symptoms for about 50 years until I figured out that a very low sugar/starch/alcohol(S) diet seemed to be relieving my symptoms. It then took approximately an additional 2 years for almost all my symptoms to clear. It then took about 6 years and a lot of serendipity to figure out what was the problem and that turned out to be only a start of a journey. I am sorry that this explanation is long but I have been told it is complicated.
It is a fact that about ½ the women in India have my gene and it leads to all the sugar problems in pregnancy. Considering my gene leads to a diagnosis of prediabetic that is what Indians told me. I quote from one nurse who said about the sugar problems in pregnancy “it must be genetic”.
Partially, because my informal interviews with a hand full of chubby Indian women are not backed up by information on Google.
I wish to help fund a study that follows the glucose tolerance tests (GTT, see footnotes 1 and 2) of women before, during and after pregnancy.
A major reason for this study is that a doctor on PBS in 2015 drew two graphs of a GTT. GTT’s run for 2 hours. The first GTT went up and then down. He indicated this is the expected GTT. The second GTT slowed its rate of assent but was still rising as he lifted his marker. The second is my GTT (2) taken in 1964. Does anyone know the name of this doctor? He defined such people as having a “hunter” gene. He said people with this GTT did not lose weight on his weight loss diet. The diabetic community says this sounds like the “thrifty” gene. Since people with the “hunter” gene should be better able to survive famines there must be a downside to this gene. I guess one downside is that women with this gene have problems controlling their blood sugar during pregnancy.
The following paragraph contains my actionable conclusions. Details describing them and what lead up to some of these conclusions follow.
Probably my most important conclusion is that Type 2 diabetes could be due to hormones used to create insulin resistance being produced all the time. Researchers where are you? Also:
In my wildest dreams this article would eventually lead to everyone getting a baseline glucose tolerance test (GTT); I strongly suggest you ask your physician to take a GTT to find out if you have the normal GTT or the “hunter” GTT.
Another dream is that doctors would publicize that you can get an autoimmune disease if you have the “hunter” gene. If you have the “hunter” gene and become chronically fatigued I suggest you see if cutting back your sugar/starch/alcohol (S) improves how you feel.
Judging from what people with reactive hypoglycemia post I have a dream that doctors will realize that what is necessary to avoid all the symptoms of either form of reactive hypoglycemia is to not let the blood sugar go above an unknown value. This value can be completely different for different people. I further guess that both types of reactive hypoglycemia are due to the same autoimmune problem. From my posts on diabetes.co.uk I conclude that the treatment for reactive hypoglycemia in the U.S. and U.K. are different. The difference comes down to, is the hunter gather diet good for humans? Do we need grains and significant fruits for a healthy diet? My personal experience indicates that a lot of small balanced meals is impractical. You are on the knife edge of going into reactive hypoglycemia.
An even bigger dream is that a very low sugar/starch/alcohol(S) diet would be tried on all type 2 diabetics and it successfully controlled high blood sugar; for some diabetics this may be a better option then the standard treatment. In that case make sure you monitor your blood sugar to see if you have cut your sugar/starch/alcohol (S) enough.
Another dream is that it would be found that people with the “hunter” gene tend to become fat on the modern diet; for me a low fat diet worked. If you have the “hunter” gene see if this works for you. As the weight loss doctor said, “people with the hunter gene do not lose weight on his weight loss diet”. This would then lead to the following obvious question. Is the hunter gene the reason for the weight problems, when they try the modern diet, with the Indian population, American Indians, Pacific Islanders etc.…? If so, all my advice follows for these people.
After years on a severe very low S diet my high blood pressure corrected itself without medication.
Is the amount of insulin produced by our diet the fundamental reason for most high blood pressure? Could a low S diet generally lead to a correction of high blood pressure?
I was interrupted by an Indian while I sprouted my theories by “½ the people of India are prediabetic (1), but they do not get diabetes”. This indicates why. I also present a theory about an alternate method of sugar storage used by some humans. I have the following question: assume a women has sugar problems during pregnancy. How can you see if her GTT has returned to normal after pregnancy if you don’t know what is her normal GTT? I have the following observation if women with the “hunter” gene are much more susceptible to sugar problems during pregnancy, maybe you can explore possible pre pregnancy interventions with these women.
In 1964 a doctor looked at my GTT and said I was prediabetic (1) and was developing insulin resistance. I am fat and have done all the wrong things, but I am not a diabetic. The reason for my GTT in 1964 is that I get low blood sugar many hours after eating too much (S). I know of 4 other people with the hunter gene who also have this symptom. We also have other symptoms starting with much lower values of (S). The symptoms are some significant degree of brain fog and fatigue. These symptoms are controlled by never letting our blood sugar go above some (unknown) value.
I theorize that the hunter gene allows people to only store sugar when their blood sugar rises above some value (3). Consider the following. Evolutionary changes are often additions to existing processes. Women with the “hunter” gene have insulin resistance in pregnancy. Insulin is needed to process protein. Look at my glucose tolerance test (2). I am led to the following weird conclusion. With the “hunter” gene people are normally in a state of insulin resistance. They are usually simulating type 2 diabetes. When their body determines that the blood sugar is heading for dangerous territory, that it will affect the general chemistry of the blood, the body cuts insulin resistance and if necessary produces insulin to keep the blood sugar from going too high. It waits over an hour in this mode and then produces enough insulin to mop up the excess sugar in the blood. My wild guess is that the “hunter” or “thrifty” gene people are constantly producing hormones to create insulin resistance (7). When the blood sugar gets too large, they stop producing these hormones and if necessary produce a little insulin, even though they are somewhat insulin resistant. After a time gap to allow the hormones to clear, they produce a large enough quantity of insulin to make most of the sugar in their blood become fat. Sometime into this insulin release they are supposed to restart the hormones. People with reactive hypoglycemia do not restart the hormones. I speculate that people with reactive hypoglycemia do not wait the necessary time if they do not have to produce insulin to prevent their blood sugar from rising too high. Their fatigue is due to not turning on the hormones which produce insulin resistance and ending up with mild low blood sugar for extended periods of time and/or trying to start the hormones. I further speculate that people with the “normal” sugar processing also use these hormones for a short time when hypoglycemia threatens. I think that people with either of the reactive hypoglycemia symptoms have disabled this response.
I am on a very low (S) diet. I am simulating a type 2 diabetic almost all the time. I speculate this was true for the hunters from which I arose.
I have reason to believe that I had an episode which was an autoimmune reaction (4). I therefore theorize that doctors should be aware that it is possible for people to have one type of cell of their adrenal glands destroyed. This compromises the possibly complicated chemistry that allows sugar to be stored based on their blood sugar in “hunter” gene people. Doctors should advise people with the reactive hypoglycemia and GTT that they will feel better if they carefully control the (S) in their diet (5). I only know of 5 people with the “hunter” gene autoimmune problem I describe and only two have had their symptoms diagnosed by doctors. The doctors noted that diet controlled their problem but had no idea what was happening. I therefore suggest that doctors make people with the hunter gene aware of this possibility.
My diet is low enough in (S) that with my hunter gene I have turned off the effects of insulin. My evidence is that my fasting blood sugar has risen, but it is very normal, because I never lower it with insulin (6). Further, on occasion, I have gained weight on this diet. I noticed that years ago I was able to lose about 80 pounds in approximately 1 year on a crash diet of pasta with cottage cheese with enough vegetables for vitamins. I also notice that I am presently losing weight on my very low (S) diet by cutting out almost all cheese. Since my meat portions are comparatively small, I assume I am losing weight for the standard reason. Further, I have no discernible problem with exercise even with my extreme diet with very low (S). My fasting blood sugar has stabilized at near the highest but normal values, ever (6). Have I returned to my hunter roots.