CoQ10, diabetes, statins

Boo1979

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Im not on statins myself so cant attest to the validity of this advice from a personal point of view but I have a relative that is an alternative health professional and ardent statin opponant. His research includes that CoQ10 is potentially a very important supplement for those who have to take statins, as well as for diabetics in general.
https://www.diabetesselfmanagement.com/blog/coq10-a-supplement-whose-time-may-have-come/
Edited to add a second link
https://examine.com/supplements/coenzyme-q10/
 
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Deanoh

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@Boo1979 Interesting,

I also read: https://www.thediabetescouncil.com/why-coq10-for-diabetes/

Effectiveness
The Natural Medicines Comprehensive Database also provides effectiveness rates. This database rates CoQ10 as likely or possibly effective for the following:

  • CoQ10 deficiency states
  • Mitochondrial encephalomyopathies— these are relatively rare disorders of the mitochondria and include:
    • MELAS: Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes
    • MERRF: Myoclonic Epilepsy with Ragged Red Fibers
  • Congestive heart failure
  • Diabetic neuropathy
  • HIV/AIDS
  • Hypertension
  • Ischemic reperfusion injury—this can occur during heart or vascular surgery
  • Migraines
  • Heart attacks
  • Parkinson’s disease
  • Peyronie’s disease- a painful and persistent erection
  • Male infertility
 

derry60

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Im not on statins myself so cant attest to the validity of this advice from a personal point of view but I have a relative that is an alternative health professional and ardent statin opponant. His research includes that CoQ10 is potentially a very important supplement for those who have to take statins, as well as for diabetics in general.
https://www.diabetesselfmanagement.com/blog/coq10-a-supplement-whose-time-may-have-come/
Edited to add a second link
https://examine.com/supplements/coenzyme-q10/
I have been taking Coenzyme Q10 with my statins for 14 years now...
 

fletchweb

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408
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Prefer not to say
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Im not on statins myself so cant attest to the validity of this advice from a personal point of view but I have a relative that is an alternative health professional and ardent statin opponant. His research includes that CoQ10 is potentially a very important supplement for those who have to take statins, as well as for diabetics in general.
https://www.diabetesselfmanagement.com/blog/coq10-a-supplement-whose-time-may-have-come/
Edited to add a second link
https://examine.com/supplements/coenzyme-q10/
I tried this last year but it didn't seem to make a difference - however most food sources that have CoQ10 is a regular part of my dietary habits and as I'm not on any Statins, I'm wondering if that may have been why I didn't notice a difference. One thing I can say - it did not appear to have any negative affects but from what I recall the supplement was expensive.
 

Sam50

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Type of diabetes
Don't have diabetes
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Diet only
Several drug companies proposed twice for a duel patent to include CoQ10 in with their statins but were turned down on account of the cost. As statins are often prescribed for long term use, I would advise taking a CoQ10 supplement they deplete the body of this enyzme and this leads to muscle wasting and eventually to congestive heart failure.

Currently reading papers on this particular enzyme as part of my Nutrition Diploma. Dr Malcolm Kendrick goes into this subject in depth x
 

DavidGrahamJones

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Several drug companies proposed twice for a duel patent to include CoQ10 in with their statins but were turned down on account of the cost.

I'm not a patent expert . . . . . . by my wife is.

Merck obtained a patent in 1990 for a statin with CoQ10 combined pill, I mention pill because it's delivery is part of the patent. https://www.functionalmedicineuniversity.com/statin-CoQ10.pdf

The way patents work means that only one entity (person, company) will obtain a patent, any further applications will be rejected because they will not pass the novelty step (there would be prior art). Obtaining a patent isn't cheap but companies like Merck will have their own attorneys in their own country and may employ other firms of patent attorneys to obtain the patent in other countries. Patents are never refused because of cost, but a company may decide not to pursue it's application because of cost, it may decide not to do anything with their patent, possibly hoping to license some other company to make the product or it might even use their patent as a way of stopping anyone else doing it.

The interesting thing about the Merck patent is that it actually mentions "impending muscle pain" as if it's a forgone conclusion. They also discuss where they are going to obtain the CoQ10 because even in 1990 it was available.

There are several countries that prescribe CoQ10 along with statins and Japan uses CoQ10 widely, especially for people who have had cardio vascular events.

In my case I found it difficult to find a suitable dose, my GP couldn't tell me because it wasn't something she could prescribe and I didn't find any relief in the side effects of statins, possibly because I didn't take enough or, as I have read, there is a question over absorption. My wife took great pleasure in recommending an alternative way of taking CoQ10 with guaranteed absorption, and that's up the backside.