Article: 'The cholesterol and calorie hypotheses are both dead.....'

[Biggles2]

This article by Dr. Malhotra, Dr. Lustig and Maryanne Demasi is well worth a read:

‘The cholesterol and calorie hypotheses are both dead — it is time to focus on the real culprit: insulin resistance’:

https://www.pharmaceutical-journal....l-culprit-insulin-resistance/20203046.article

 

[Guzzler]

Good article, thanks for posting. I especially liked the stats on TOFIs.

 

[hankjam]

Given that statins can give the illusion of CVD protection, predispose the development of type 2 diabetes in up to 1 in 50 patients taking these drugs, and cause reversible side effects in up to 29% of users, stopping statins may paradoxically ‘save more lives’ and improve quality of life in those taking them[15].

So glad I took them for so many years.....

 

[zand]

Thanks, good info there.

 

[NicoleC1971]

I see many people aged over 60 and taking statins who truly believe that their 'high cholesterol' is no longer a problem because they are taking statins. I hope that doctors will start to discuss the risks and benefits more clearly in the future.

 

[bulkbiker]

I see many people aged over 60 and taking statins who truly believe that their 'high cholesterol' is no longer a problem because they are taking statins. I hope that doctors will start to discuss the risks and benefits more clearly in the future.

Sad thing is their "high cholesterol" was probably never a problem in the first place...

 

[PenguinMum]

Good article, easy to understand. Strengthens my resolve to avoid statins.

 

[eggs11]

Thanks @Biggles2 a really interesting article.

 

[pdmjoker]

I especially liked the stats on TOFIs

@Guzzler What are TOFIs?

 

[JohnEGreen]

@Guzzler What are TOFIs?

Question not addressed to me but here is an answer any way

TOFI (thin-outside-fat-inside) is used to describe lean individuals with a disproportionate amount of fat (adipose tissue) stored in their abdomen.

 

[Guzzler]

Question not addressed to me but here is an answer any way

TOFI (thin-outside-fat-inside) is used to describe lean individuals with a disproportionate amount of fat (adipose tissue) stored in their abdomen.

Slight difference, I think, the TOFIs have their fats stored mostly around the organs.

 

[Guzzler]

@Guzzler What are TOFIs?

TOFI as answered by JohnEGreen also known as MONW i.e Metabolically Obese Normal Weight.

 

[Biggles2]

I especially liked the stats on TOFIs.

I knew you would @Guzzler!

 

[Guzzler]

I knew you would @Guzzler!

Gotta debunk the myths, lass

 

[pdmjoker]

TOFI (thin-outside-fat-inside) is used to describe lean individuals with a disproportionate amount of fat (adipose tissue) stored in their abdomen.

Thanks!

 

[JohnEGreen]

Slight difference, I think, the TOFIs have their fats stored mostly around the organs.

I take your point, but most of the organs in question are situated where?

 

[Guzzler]

I take your point, but most of the organs in question are situated where?

The important ones for us are the heart, liver and pancreas. The kidneys do require a little extra padding as they are not afforded much protection from the ribs. The abdominal organs and of course the gut are just not places in TOFIs where much adipose tissue is stored so belly fat or beer belly is something I have never had even after having three children. Hopefully, the little weight that I have lost will be from around the organs and possibly the adipose tissue in the muscles, without testing I shall never know.

 

[JohnEGreen]

The abdomen contains all the digestive organs, including the stomach, small and large intestines, pancreas, liver, and gallbladder. These organs are held together loosely by connecting tissues (mesentery) that allow them to expand and to slide against each other. The abdomen also contains the kidneys and spleen

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity behind the stomach. It is an endocrine gland producing several important hormones, including insulin, glucagon, somatostatin, and pancreatic polypeptide

And yes I know you can also have fat around the heart as well

 

[Guzzler]

Y

The abdomen contains all the digestive organs, including the stomach, small and large intestines, pancreas, liver, and gallbladder. These organs are held together loosely by connecting tissues (mesentery) that allow them to expand and to slide against each other. The abdomen also contains the kidneys and spleen

The pancreas is a glandular organ in the digestive system and endocrine system of vertebrates. In humans, it is located in the abdominal cavity behind the stomach. It is an endocrine gland producing several important hormones, including insulin, glucagon, somatostatin, and pancreatic polypeptide

Yes, I am aware.