Does anyone know how long it takes:
1) type 1 to develop from immune recognition of the beta cells to their destruction eg a cold normally passes in 2 weeks, but the development is longer?
2) type 2 to develop: is it present from birth but only manifests itself under certain conditions.
Thanks.
Hard to say, but I can try.
1) The incubation time from when your antigens
starts to destroy beta cells the first time until you get full blown type 1 diabetes vary, so there is no correct answere to that question.
The immune system is weaker the younger you are, so type 1 in kids develope much faster than what type 1(lada) does in adults.
Also, the destruction of beta cells can go in phases, meaning the antigens aren’t positive or active all the time (reason that some type 1 diabetics doesn’t test positive for antigens when first diagnosed).
A friend of mine got diabetes as a little kid, and it took 4-6 months from his first symptoms until he got diagnosed. But it is hard to tell, because none diabetic can pin point to the exact moment when beta cell destruction first started.
But a diabetic GP told me that your body will function like normal even as you slowely lose all of your beta cells. It isn’t before you lose/have lost 80% or more of your beta cells that you start to get really ill, and need emergency help. Some type 1 diabetics doesn’t get really ill before they got till that point, when others can get some of the symptoms way before they have lost that many of their beta cells.
Only thing sure is, when an undiagnosed type 1 have lost most of his/her beta cells it will go downward pretty fast, as little as a week can be difference between life and death.
2) Type 2 is usually linked with metabolic syndrome. The criterias for metabolic syndrom are elevated levels of triglycides, high blood pressure, lower levels of HDL cholesterole and obesity.
It is believed that you have to be genetically available to get the disease (usually runs greater risk of type 2 if you have it in your family or previous generation), but type 2 is a disease of affluence. Meaning there has to be something in your environment or lifestyle that triggers developement of the disease. Common here can be little to no training, a bad or poor diet, overweight etc.
With that said, there is a few other conditions that can give permanent blood sugar problems or develope to diabetes. Different types of mody, drug or steroid induced diabetes, malfunction in the pancreas do to other conditions, or RH. Diabetes are a complex disease and can manifest itself very diffrently form person to person.