Mounjaro or Metformin causing me problems?

[Gozza33]

Hi all
Nearly 3 weeks ago, I was put on 2.5mg Mounjaro and initially things were OK. Although there was the initial feeling of being washed out the day after I had taken a jab, generally to start with, side effects were simple like manageable nausea and one or two loose stomach issues. Sugars are right down from 9 to 5.6 and I have lost 6lbs. However since starting, I was also told to stop Sitagliptin and increase my Metformin CR tablets to 4 a day. Metformin has never worked well with me causing serious stomach issues but these past 3 days I have had terrible stomach issues again leaving me never far from a toilet.
I have decided to monitor my sugars closely and reduce my Metformin back to 2 a day in the hope it helps to settle my stomach as I know there is a direct link between Metformin and my stomach issues in the past.
I am intrigued as to what others' thoughts might be? Have any of you had similar experiences? I know when I get to my 3 month review I will certainly be discussing this but maybe I should go to the Dr sooner?

 

[Deleted member 596235]

Hi all
Nearly 3 weeks ago, I was put on 2.5mg Mounjaro and initially things were OK. Although there was the initial feeling of being washed out the day after I had taken a jab, generally to start with, side effects were simple like manageable nausea and one or two loose stomach issues. Sugars are right down from 9 to 5.6 and I have lost 6lbs. However since starting, I was also told to stop Sitagliptin and increase my Metformin CR tablets to 4 a day. Metformin has never worked well with me causing serious stomach issues but these past 3 days I have had terrible stomach issues again leaving me never far from a toilet.
I have decided to monitor my sugars closely and reduce my Metformin back to 2 a day in the hope it helps to settle my stomach as I know there is a direct link between Metformin and my stomach issues in the past.
I am intrigued as to what others' thoughts might be? Have any of you had similar experiences? I know when I get to my 3 month review I will certainly be discussing this but maybe I should go to the Dr sooner?

Hi there Gozza...

I note that you're (apparently?) not seeing your doctor until
you're due a 3-month review. Can I ask who said "... to stop
Sitagliptin and increase my Metformin CR tablets to 4 a day"?

Briefly, I'd say, yes, by all means see your doctor as soon as
possible, as your medications are obviously causing you some
degree of distress—both physically and emotionally.

Take care.

 

[Gozza33]

Hi there Gozza...

I note that you're (apparently?) not seeing your doctor until
you're due a 3-month review. Can I ask who said "... to stop
Sitagliptin and increase my Metformin CR tablets to 4 a day"?

Briefly, I'd say, yes, by all means see your doctor as soon as
possible, as your medications are obviously causing you some
degree of distress—both physically and emotionally.

Take care.

Hi AusGeoff

So it was the diabetic specialist at the surgery that stated my next review is 3 months in. She also said that Sitagliptin should not be taken with MJ so that it why it was dropped and the Metformin increased. 4 days ago I decided to go back to my old dosage of 2 Metformin a day and so far, my sugars have remained controlled and my stomach distresses have ceased - which works for me as it means my day to day life is no longer disrupted to the same level.
I am starting 5mg this Saturday so if things continue to go as they are, I am happy. Weight is steadily dropping at a healthy rate so all good in my mind.