From my personal experience, because the pancreas is compromised and gliclazide works by stimulating the pancreas, gliclazide did little to control my blood sugars. Quadrupling the dose made no difference to my blood sugars and I ended up on insulin.
Hi, I’ve been down a similar route after having a modified whipple operation. Initially, I was on metoformin and linagliptin. The linagliptin was stopped due to possible negative affects on the pancreas and I was put onto gliclazide. Despite a couple of dose increase of gliclazide, it made...