The liver is the regulator.hi there
What is the relationship of insulin with carbohydrates
I mean the use of diet reduces the production of insulin
They don't. Their livers do. Their pituitary gland does too. Their guts do. Their genes do too.Good morning @kitedoc and @ickihun and have a nice day In fact first thank you for this valuable information It seems that insulin production needs to eat carbohydrates
That's why I am surprised by some people who eat a lot of carbohydrates but with physical efforts they control the level of blood sugar
But on what substance the pancreas depends on the production of insulin do you have any informations about itThey don't. Their livers do. Their pituitary gland does too. Their guts do. Their genes do too.
The pancreas just creates the hormone from all the signals.
Maybe nerve signals but definitely other hormones in the mix.
But on what substance the pancreas depends on the production of insulin do you have any informations about it
Thank you Madam, does the pancreas use any substances?The pancreatic beta cells in the Islets of Langerhans.
Healthy cells produce the hormone insulin. Damaged cells don't (type1).But on what substance the pancreas depends on the production of insulin do you have any informations about it
Hi @DCUKMod@HICHAM_T2 - As I understand it, you are looking after your T2 by using diet and some exercise. Just recently,you seem to have become very, very interested in insulin. Is there any particular reason? Is anything worrying you?
Hi"That's why I am surprised by some people who eat a lot of carbohydrates but with physical efforts they control the level of blood sugar"
That is because on every muscle and skeletal cell are specific glucose transporters (GLUT 4 ) that admit glucose into the cell for use as energy. These are brought to the surface of the cell when insulin binds to an insulin receptor on the outside surface of the cell (i.e they ate stimulated into action by the presence of insulin.)They open gateways in the cell membrane to admit glucose into the cell.
During exercise the cells quickly use up their reserves of energy and two things happen
1) the insulin receptors become more sensitive to insulin i.e. less is needed to stimulate the GLUT 4 transporter to move to the surface of the cell. This effect continues for a period after exercise (i.e the cells become more sensitive to insulin)
2) Muscle contractions themselves use a different pathway to signal transporters to move to the surface of the cell .(i.e. without insulin)
For a simple outline of how it works and why it helps in T2 and can help but also cause problems for those who use insulin
http://www.diabetesforecast.org/2010/jul/the-science-of-exercise.html
This video shows what is going on at the cellular level (quite complex but the graphics help explain)