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600 calories to "reverse" Type2

Discussion in 'Type 2 Diabetes' started by catherinecherub, Jun 24, 2011.

  1. catherinecherub

    catherinecherub · Guest

    Interesting article here. DUK funded the study.

    600 calories is a near starvation diet and you would have to be sedentary, almost immobile I should think, to put this into practise.

    http://www.dailymail.co.uk/health/artic ... ds-newsxml

    Warning - Don't try this at home without your Dr's consent.
     
  2. josie38

    josie38 · Well-Known Member

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    Hi catherinecherub,

    I read this article with interest but i dont think they could recommend it as they only did it on 11 people which for me is not a big indicator of it working. My big question would be what happens when they return to their normal eating habits does it come back! If getting t2 is not incentive enough to help them get healthier lifestyles on their own then i dont know what will

    josie
     
  3. noblehead

    noblehead Type 1 · Guru
    Retired Moderator

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    Reading the article on DUK it says they were on a follow-up diet after pancreatic function had been restored but it doesn't say what this was or what the maximum calories were, interesting article non the less.

    Nigel
     
  4. josie38

    josie38 · Well-Known Member

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    Hi nigel,

    I was a bit puzzled by no mention of what the follow up diet was or maximum calories. I agree is was interesting to read.

    josie
     
  5. Patch

    Patch Type 2 · Well-Known Member

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    Sounds a little like the "Lighter Life" Diet. I know a few people who have had great success on that diet, losing over 3st each. (None are diabetic, though...)

    I'd LOVE to know where those 600 calkories came from. I'd certainly give this a try!
     
  6. noblehead

    noblehead Type 1 · Guru
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    It says on DUK that it was a liquid diet and non-starchy vegetables.... that's all the article says!

    Nigel
     
  7. ebony321

    ebony321 · Well-Known Member

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    This is just being announced on Viking FM!
     
  8. Funky Mum

    Funky Mum · Well-Known Member

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    Sounds interesting! I did Cambridge a while back and lost 30lbs but had some emotional eating issues and ended up back where I started.
    I'm tempted to give this another go.
     
  9. ebony321

    ebony321 · Well-Known Member

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    Again the word 'reverse' is used incorrectly.

    It's not exactly 'reversed' if you still have to follow a diet afterward to maintain BG levels, if it was 'reversed' then you'd be able to tolerate foods like someone without diabetes. :?
     
  10. phil2440

    phil2440 Type 2 · Member

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    Hmmm - 11 people is way to small a sample to be making the statement that this wonder diet "reverses" T2 Diabetes. The article doesn't mention how much weight the subjects lost, which may be more of a cause than this particular diet. The lack of certain nutrients in the diet may be the cause of the pancreatic cells reactivating, which would be a valuable route of further research.
     
  11. catherinecherub

    catherinecherub · Guest

    I haven't read the DUK. On this diet they would probably have been medically supervised throughout as it is such a low calorie one. I remember when the liquid diets came along and everyone was raving about them. A lot of people fell by the wayside in a very short time and then had to be so careful when they started eating properly again that they didn't overdo it.
    Diabetics need a plan that lasts a lifetime and as food should be enjoyable, not a chore, it would defeat the purpose.
     
  12. BAZZA_P

    BAZZA_P · Well-Known Member

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    Interesting but surely not a cure - 1 week seems a bit fast! Maybe they might be able to use this research to come up with some very good drugs to help diabetes though
     
  13. catherinecherub

    catherinecherub · Guest

  14. ClaireG 06

    ClaireG 06 · Well-Known Member

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    I agree, very interesting but we need to know a lot more and eleven people is far to few to really know if it works or not.
     
  15. the_exile

    the_exile · Well-Known Member

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    BBC Story on Type 2 reversal

    Nice to see them differentiate between the two types as per usual, particularly enjoyed this bit....

    Professor Edwin Gale, a diabetes expert from the University of Bristol, said the study did not reveal anything new.

    "We have known that starvation is a good cure for diabetes. If we introduced rationing tomorrow, then we could get rid of diabetes in this country."

    Full article here, interesting reading, feel kind of guilty reading it whilst munching on a toffee crisp which my humalog will take care of :lol: http://www.bbc.co.uk/news/health-13887909
     
  16. catherinecherub

    catherinecherub · Guest

    Re: BBC Story on Type 2 reversal

    Doesn't really ring true.
    Slim people can get Type 2 diabetes and there were Type 2's around when rationing was around admittedly in the older age group.. There is more to Type 2 than overeating. :roll:
     
  17. the_exile

    the_exile · Well-Known Member

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    Re: BBC Story on Type 2 reversal

    Yep, friend of the family is type 2 and she's as healthy as you can get, fit, eats well etc, hope the media's bandwagon is big enough for them all to jump on!

    Edit: Just noticed there's already a thread on this on the type 2 board 8)
     
  18. desertbear42

    desertbear42 · Member

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  19. ally5555

    ally5555 · Well-Known Member

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    Interesting - as a newly qualified dietitian we had patients admitted to a ward to try and kick start wt loss using 600 calories. It would mean 2 small protein portions , a small CHO portion, a scrape of spread, 2 fruit, veggies and a small amount of milk. That is starvation!
    They all had supplements

    I remember pts found it very difficult to follow. But if it kick starts a change in insulin sensitivity maybe it has some worth - need to read the whole paper and look at what the participants were eating previously!
    Ally
     
  20. phoenix

    phoenix Type 1 · Expert

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    As Catherine says, don't try this at home folks , these people were carefully monitored and a 600 cal diet is extremely low.
    but it is very interesting
    http://www.springerlink.com/content/68r ... lltext.pdf
    First the subjects; type 2 diabetes (age 35– 65 years,
    HbA1c 6.5–9.0% [48–75 mmol/mol],
    diabetes duration <4 years,
    stable BMI 25–45 kg/m2). ( my comment:this would exclude the 'thin' 'type 2s')
    None of them were on insulin or had any other problems.

    There were 15 subjects, 3 did not comply with the diet and one dropped out for an unrelated medical reason so 11 finished it.

    The actual diet was basically liquid based (510 calories) 46.4% carbohydrate, 32.5% protein and 20.1% fat; vitamins, minerals and trace elements; supplemented by 3 portions of non starchy vegetables to make up the remaining 90 calories.
    I make that as 59g carb, 45g proten. 11.3g fat + whatever is in the veggies .

    The return to normal diet :
    An OGTT was done 12 weeks after the diet ie at 20 weeks since the start. Of the 11: 1 couldn't do the test for unrelated reasons, 3 had returned to diabetic results (ie above 11mmol after glucose challenge) but the others 'passed' the OGTT.


    There are a lot of interesting bits in the results. The fasting glucose dropped after the first week. The C peptide (showing how much insulin is being produced) dropped over the 8 weeks, trigs dropped a lot. The circulating fatty acids rose initially (and the liver function test showed a biref deterioration) but then steadily improved. At 20 weeks these levels had dropped further still.

    The authors say
    There is a lot in the discussion section about the role of fats in the organs and free fatty acids in circulation. There is aso some discussion about the genetic susceptibility to 'pancreatic fat accumulation in terms of inhibition of glucose-dependent insulin secretion.'

    There are limitations
    1) the numbers involved, though they say the low numbers meant it could be a carefully controlled study and also so that they could use MRI scans to determine liver and pancreatic fat.
    2) I think that due to the limltations of MRI scans in measuring the pancreatic fat.
    They can't actually look at the fat in the insulin producing islets and that this would be better but animal studies suggest the amount of fat in the islets and pancreas are related.
    3)People had only had diabetes diagnosed for a short time. It doesn't necessarily apply to people who have had it for longer. (further studies etc)
    4) There needs to be longer follow up after return to normal diet.

    Conclusion
    .
     
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