Hey Wgc2017, I don't know about that particular antidepressant, but I found that most antidepressants I was put on made me outrageously hungry for carbs, so yes, affected my blood sugars! Just be mindful if you find yourself wanting to eat all the time or obssessed about food!! Thankfully I am no longer on them, but it took many years and much counseling to get me to that point. Blessings/L