Apidra and Tresiba

[Jason_Avoneg]

Hi all,

I made the switch to Apidra and Tresiba from NovoRapid and Levemir.

It's not been a good switch so I wanted to see if it's just me...

Tresiba - it's eerily unnoticeable, i.e. I can take up to 40 units and never feel a hypo and be fine all day long without eating...I guess that's right if my body is making use of the insulin but it feels like it's not almost working. I've upped my doses to 40 units and it's been a couple of months now and I'm wondering why I'm taking so much...

Apidra - same thing, compared to NovoRapid I'm taking like 3 times the amount and the reason I opted for it is because it's allegedly the fastest acting insulin...I'm finding it does nothing for around an hour then slowly seeps in...but I'm literally going through like 80 units a day and still have terrible control...

Luckily I've got a bunch of NovoRapid left over so I'm going to switch back.

The Tresiba I like it's very linear profile (assuming it's doing something...) With levemir I use to experience random dips.

In short has anyone else found Apidra to be ineffective or no way as fast as it should be?

 

[tim2000s]

Hi all,

I made the switch to Apidra and Tresiba from NovoRapid and Levemir.

It's not been a good switch so I wanted to see if it's just me...

Tresiba - it's eerily unnoticeable, i.e. I can take up to 40 units and never feel a hypo and be fine all day long without eating...I guess that's right if my body is making use of the insulin but it feels like it's not almost working. I've upped my doses to 40 units and it's been a couple of months now and I'm wondering why I'm taking so much...

Apidra - same thing, compared to NovoRapid I'm taking like 3 times the amount and the reason I opted for it is because it's allegedly the fastest acting insulin...I'm finding it does nothing for around an hour then slowly seeps in...but I'm literally going through like 80 units a day and still have terrible control...

Luckily I've got a bunch of NovoRapid left over so I'm going to switch back.

The Tresiba I like it's very linear profile (assuming it's doing something...) With levemir I use to experience random dips.

In short has anyone else found Apidra to be ineffective or no way as fast as it should be?

Hi Jason,

There are a fair number of reports of users not getting the effects they expected out there on the internet, and many don't see anything faster than Novorapid, so you aren't alone.

 

[SimonCrox]

Apidra and novorpid and humalog are all much the same; the differences between them are trivial - the only significant differences are the pens, so I would suggest using whatever you prefer. There is a new Fast Insulin Aspart (Fast novorapid - not sure of tradename) that is faster still and has some advantages in terms of HbA1c reduction vs novorapid, but possibly more hypos after meals.
But the fact that you are not getting hypos is good news, despite the number of units; are your glucose levels OK? Do you have type 1 or type 2 diabetes?
Levemir is a bit weaker than the other insulins, eg one study got same glucose outcomes levemir vs lantus, but folk used 50% more levemir than lantus. Were your glucose levels controlled on the levemir? I have seen tohers who found the Tresiba did very little, despite trying several different packs lest it had been damaged in the heat of the British summer.
At the end of the day, everyone is different, so one would use whatever suited.
best wishes

 

[karen8967]

im on apidra of a day i find also that it takes about an hour to start working on me i also get like a big spurt around the 3 hour mark b4 it tails off .

 

[Jason_Avoneg]

Hey Simon, thanks for the response. My glucose levels aren't ok, I got complement after progressing my career and not going to the gym and etc. So I'm back to basics sorting it all out again. I'm a T1.

NovoRapid is far superior to Apidra in my experience, and thanks for informing me of the new faster insulin I'm going to look into that.

I've got good hypo awareness, so tend to err on the side of caution and run higher bs when in doubt...

I've bought a libre freestyle and so I'm regaining control again. Not sure whether I'll get NHS funding, but I've decided I'll personally fund it if not as I can't really stab my finger at work multiple times a day as I'm in and out of meetings a fair bit.

Thanks again, your comment is helpful.