well if it is genes that rules my maternal side out of the running but that makes a nonsence of the risk percentages as my generation is a 100% diabetes hit. The eldest of the next generation is only 27 so too early to tell. How can I work out the liklihood of an only child (dad) of an only child of an only child from the liklihood of it being from one of their spouses who were one of 3, 14, 3first marriage 9 secondmarriage of a father who was one of three? The next generation back was Mary who had a brother who died aged 20. Strangely their locations were all coastal. Liverpool, Pembroke, Ripple in Kent and the plains between Aberystwyth and Dolgellau. If anybody wants to research the Jones family of Merionethshire please be my guest.I have a nephew who is diabetic (type 2) but I am suspicious since his family seem to get diagnosed with anything that gives free prescriptions or blue passes and stuff. I don't subscribe to the blood relative theory. If the popular opinion is that we brought it on ourselves by stuffing our faces and becoming fat gits then where do genes fit into that scenario? It's make your mind up time. genes or fat git, which is it.
my generation is a 100% diabetes hit.
Yes..............and no.in your family?
I am grateful also things are much better today.As far as I know none of my immediate family have been diagnosed so I'm the odd bod who doesn't eat or drink "normal" food at family buffets. My mother in law was diabetic in the days before drugs and self testing were available and had a very restricted and miserable diet. She suffered with and died from heart problems which were probably related to the untreated diabetes? So now, when I start to moan about taking my pills and testing my bloods I remind myself how much better things are today and be grateful.
One cousin and I were how we ate related only , -no other diabetics , although some dont believe in this and not sure if I believeI certainly ate a lot of bread but there is nothing I can pinpoint. IMHO I unscientifically believe food is a factor. The brother who got diagnosed first ate **** and the one who has the lowest hba1c is married to a vegetarian who has been vegan on ocassion. My downfall is that when I was ill I saved all my energy for work and relied on hubby to shop and sort out meals. He does not cook so we ended up with a lot of chips and he bought me treats to show he cared. In hindsight a few less pecan and maple syrup danish would have been advisable. The rugby playing nephews regularly bring chips and pizza home and that sister is verging on the edge of full blown but her GP has said he will prescribe medication and her soon to be daughter in law T1 is advising her. Sister is certain to be T2 but she works for the NHS and has colleagues with diabetes so she is in a better place to know than I am.
There is absolutely no sign of it on my mums side (she is one of three all of whom have had children) and apart from her mother always using stork margarine and my parents butter I was raised on pretty much the same food as my mum was bearing in mind both parents were schoolchildren during WWII rationing. We ate a lot of homegrown veg as presumably did the generations before as their market garden was acquired in 1892 (mums paternal side). Mums maternal grandparents were both from large families.
My father was in the food industry and took a very dim view of the convenience food sector but and this is a biggie do remember DDT was not banned in the UK until 1984. Many years after it was banned in the US and several other countries.That is why I went organic when I got my only plot.
If it is genetic from the Pembroke familiy there will be a diabetes hotspot in a village called Camrose. It is more difficult to make such an assertive statement about the family from Northborne near Ripple but the children that survived infancy all lived to a ripe old age and there is no indication of it there. The mariner from Liverpool only had three offspring but the son in question had 12 who all lived to a good age . If it is genetic I think the Jones family is the first one to investigate. The descendents of John Jones of Llanycil married the descendents of Hugh Jones of LLanyllwy???/ lets call it aberystwyth before Aberystwyth was built. Lol. If from that info I discover I have lots of cousins on here it would seem there is a clear genetic influence.
I never played a lot of sport but I walked a lot and was generally active. Much the same can be said about my siblings. Then I developed a problem walking about 8 years ago and got a diagnosis of arthritis of the hip last week. I am sure that has had a bearing on matters.
It will be great to discover the diabetes trigger points .
Exeter university have some pretty convincing results indicating a genetic predisposition so I am more convinced than you seem to be. To my mind that could allow it to be traced to the equivialent of the viking gene in carpal tunnel syndrome . If that is the case DNA testing should be able to indicate who is at risk so that they have the opportunity to make lifestyle modifications. I imagine the scentists would need some very convincing collaberative data in order to succeed in a bid to fund that research. That is why I went into such boring detail. Something may trigger a link leading to a high probality indicator especially has so many people have done their family tree nowadays. I never heard what the outcome of Camerons genome sequencing project is. That could produce evidence of a genetic link and that would allow scientists to start isolating the trigger mechanisms.One cousin and I were how we ate related only , -no other diabetics , although some dont believe in this and not sure if I believe
My 10yr old gives blood for dna for researchers in cambridge for genetic diseases. Leptin is their interest, mainly.Yin yes..............and no.
Grandmother - dead
Father (same family) in denial
Me - T2 since Oct 15
My kids - I've been told to keep an eye on them - I've noticed that they get up to go to the toilet at night - only 17 years old. They are being tested.
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