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article in the sun 20/11/08
- Thread starter chris1960
- Start Date
sugarless sue
Master
Sounds good but...the Sun is not exactly the most accurate paper in the World! :roll:
hi sue i can see your scepticism about the sun news paper but there are a lot of articles on the net in reference to this ie some stuff from yahoo news about an article from singapore saying the same things ? below is an article produced yesterday 20/11/08
SINGAPORE: Pure insulin—producing cells, similar to those found in the human pancreas, have been developed in the lab by a team of Singapore researchers working with mouse embryonic stem cells.
The breakthrough, which will be key in treating diabetes, was achieved by Dr Lim Sai Kiang from the Institute of Medical Biology (IMB) and Dr Li Guodong from the National University Medical Institutes, Yong Loo Lin School of Medicine at National University of Singapore.
The researchers were able to develop an unlimited number of pure insulin—producing cells, which when transplanted into diabetic mice caused the high blood glucose levels of the animals to drop.
The experiments also showed that when the transplanted cells were later removed from the diabetic mice, the blood glucose remained normal as well as the insulin—production and glucose—sensing capacity in the mice.
Another discovery was that none of the diabetic mice involved in the transplants developed teratoma, a type of tumour which usually occurs with the use embryonic stem cells and complicates treatment.
The research provides proof that the method of treatment could be used for diabetic people who need pure insulin—producing cells.
Professor Gordon Weir, Director of the Clinical Islet Transplantation Program at Harvard Medical School, has described the work by the researchers as "impressive".
"We need something to put into diabetic patients to treat their condition, and these findings tell us interesting things about the development of beta cells," said Professor Weir, who also holds appointments at the Harvard Stem Cell Institute and Joslin Diabetes Centre.
Speaking of his work, Dr Lim said that what is also significant is the chance for further studies in the treatment for diabetes as the researchers can isolate and then multiply insulin—producing cells from different embryonic stem cells for an unlimited supply of pure insulin—producing cells which they can study.
Dr Li added, "Besides providing a tool to facilitate basic research in test tubes and animals, these insulin—producing cells may be also used to replace the isolated native pancreatic cells that are hard to obtain in a large amount, for pharmacological tests."
The work of Dr Lim and Dr Li, which has been published in two separate papers, has been recognised as one of the "Novel and Newsworthy Top Ten" in Cell Biology at the an American Society for Cell Biology (ASCB).
— CNA/sf
SINGAPORE: Pure insulin—producing cells, similar to those found in the human pancreas, have been developed in the lab by a team of Singapore researchers working with mouse embryonic stem cells.
The breakthrough, which will be key in treating diabetes, was achieved by Dr Lim Sai Kiang from the Institute of Medical Biology (IMB) and Dr Li Guodong from the National University Medical Institutes, Yong Loo Lin School of Medicine at National University of Singapore.
The researchers were able to develop an unlimited number of pure insulin—producing cells, which when transplanted into diabetic mice caused the high blood glucose levels of the animals to drop.
The experiments also showed that when the transplanted cells were later removed from the diabetic mice, the blood glucose remained normal as well as the insulin—production and glucose—sensing capacity in the mice.
Another discovery was that none of the diabetic mice involved in the transplants developed teratoma, a type of tumour which usually occurs with the use embryonic stem cells and complicates treatment.
The research provides proof that the method of treatment could be used for diabetic people who need pure insulin—producing cells.
Professor Gordon Weir, Director of the Clinical Islet Transplantation Program at Harvard Medical School, has described the work by the researchers as "impressive".
"We need something to put into diabetic patients to treat their condition, and these findings tell us interesting things about the development of beta cells," said Professor Weir, who also holds appointments at the Harvard Stem Cell Institute and Joslin Diabetes Centre.
Speaking of his work, Dr Lim said that what is also significant is the chance for further studies in the treatment for diabetes as the researchers can isolate and then multiply insulin—producing cells from different embryonic stem cells for an unlimited supply of pure insulin—producing cells which they can study.
Dr Li added, "Besides providing a tool to facilitate basic research in test tubes and animals, these insulin—producing cells may be also used to replace the isolated native pancreatic cells that are hard to obtain in a large amount, for pharmacological tests."
The work of Dr Lim and Dr Li, which has been published in two separate papers, has been recognised as one of the "Novel and Newsworthy Top Ten" in Cell Biology at the an American Society for Cell Biology (ASCB).
— CNA/sf
sugarless sue
Master
Stem cell research is definitely the way forward for a lot of conditions.
Hi
Have seen stem cell research made reference to lots of times in context of diabetes but the problems have historically been the immunosuppressive drugs required thereafter. Obv problem being suppression of the immune system in someone prone to autoimmune conditions - medical catch 22 (or bloody Sods Law more like)
I joked to the head DSN that she should be extracting cells from my pancreas whilst still in honeymoon so they could be used for cloning or stem cells but she did not have a clue what i was talking about.
Suppose mind you, a cure is not in HER vested interest, what with it being the basis of her job and all ..........................
Have seen stem cell research made reference to lots of times in context of diabetes but the problems have historically been the immunosuppressive drugs required thereafter. Obv problem being suppression of the immune system in someone prone to autoimmune conditions - medical catch 22 (or bloody Sods Law more like)
I joked to the head DSN that she should be extracting cells from my pancreas whilst still in honeymoon so they could be used for cloning or stem cells but she did not have a clue what i was talking about.
Suppose mind you, a cure is not in HER vested interest, what with it being the basis of her job and all ..........................
Veryfew people understand stem cells.Me included 
The only ones I've actually had experience of were in the root tips of onions. I don't know much about them
Stem cells are undifferentiated cells, which have the potential to develop into a variety of specialist cells.
The cells of early embryos are stem cells, which left to nature will differentiate into all the kinds required to build an adult of their own species. Those that KNOW can make stem cells develop into cells to take the place of cells which are failing, hence nerve cells for treatment of degenerative motor nerve or sensory nerve disorders and brain cells for conditions like Parkinsons and Alzheimers. Skin cells for burn repair, which is one that I think will happen. and cells to change into beta cells for T1 diabetes. And cells to replace lost T cells in HIV( which may already have been done)
We all produce some stem cells of our own. If these can be iduced to turn into something we need, there will be the advantage of having cells which will not trigger an immune response and therefore will not need immunosuppressive drugs. Our immune systems can recognise "stranger" cells.
When organ transplsntation was first tried, it was the immune response which was the biggest problem. Now we have a team that has seeded a transplan torgan with a patient's own cells, so that hte recipient does not need immunosuppression. The medics on this forum can probably explain all this more exactly. I'm a mere science teacher.(retired, but not switched off)
The only ones I've actually had experience of were in the root tips of onions. I don't know much about themStem cells are undifferentiated cells, which have the potential to develop into a variety of specialist cells.
The cells of early embryos are stem cells, which left to nature will differentiate into all the kinds required to build an adult of their own species. Those that KNOW can make stem cells develop into cells to take the place of cells which are failing, hence nerve cells for treatment of degenerative motor nerve or sensory nerve disorders and brain cells for conditions like Parkinsons and Alzheimers. Skin cells for burn repair, which is one that I think will happen. and cells to change into beta cells for T1 diabetes. And cells to replace lost T cells in HIV( which may already have been done)
We all produce some stem cells of our own. If these can be iduced to turn into something we need, there will be the advantage of having cells which will not trigger an immune response and therefore will not need immunosuppressive drugs. Our immune systems can recognise "stranger" cells.
When organ transplsntation was first tried, it was the immune response which was the biggest problem. Now we have a team that has seeded a transplan torgan with a patient's own cells, so that hte recipient does not need immunosuppression. The medics on this forum can probably explain all this more exactly. I'm a mere science teacher.(retired, but not switched off)
