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Here is a link to an article on the DUK website recently:
http://www.diabetes.org.uk/About_us/New ... -diabetes/
As a paid up member of DUK I came across this little gem about a Grapefruit ingredient and it's possible beneficial effects for Type 2 Diabetics. I read this and was startled as Grapefruit and it's juice can be deadly to anyone who is taking certain Statin's. As many type 2's are automatically put on Statin's when diagnosed members who love eating Grapefruit need to be aware of the danger. The particular ingredient mentioned may well turn out to be safe, but Grapefruit is certainly not for some people. Me being one of them !!!
Here is a series of extracts from an article about this subject:
Although eating fruit may seem harmless, drinking a glass of grapefruit juice or eating a grapefruit around the time you take your statin may be deadly.
Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.
When grapefruit juice is consumed at or around the time you take your statin, the components in grapefruit prevent these enzyme systems from breaking down the drug, causing the drug to accumulate in high amounts in the body. This can be very dangerous and can cause a variety of health problems, such as liver damage or a rare condition called rhabdomyolysis (severe muscle and kidney damage).
So far, the only statins significantly affected by this interaction are:
atorvastatin (Lipitor®)
lovastatin (Mevacor®)
simvastatin (Zocor®)
Other statins do not seem to demonstrate the same, profound effect with grapefruit as seen with the other statins. These would include:
rosuvastatin (Crestor®)
pravastatin (Pravachol ®)
fluvastatin (Lescol ®)
For the full article - here is the link:
http://cholesterol.about.com/od/statind ... itstat.htm
Ken.
http://www.diabetes.org.uk/About_us/New ... -diabetes/
As a paid up member of DUK I came across this little gem about a Grapefruit ingredient and it's possible beneficial effects for Type 2 Diabetics. I read this and was startled as Grapefruit and it's juice can be deadly to anyone who is taking certain Statin's. As many type 2's are automatically put on Statin's when diagnosed members who love eating Grapefruit need to be aware of the danger. The particular ingredient mentioned may well turn out to be safe, but Grapefruit is certainly not for some people. Me being one of them !!!
Here is a series of extracts from an article about this subject:
Although eating fruit may seem harmless, drinking a glass of grapefruit juice or eating a grapefruit around the time you take your statin may be deadly.
Grapefruit contains the compound bergamottin, which interacts with certain enzyme systems in the body, such as cytochrome P-450 and P-glycoprotein. These enzyme systems are responsible for breaking down statins, as well as other drugs, into more usable chemicals and transporting them in the body.
When grapefruit juice is consumed at or around the time you take your statin, the components in grapefruit prevent these enzyme systems from breaking down the drug, causing the drug to accumulate in high amounts in the body. This can be very dangerous and can cause a variety of health problems, such as liver damage or a rare condition called rhabdomyolysis (severe muscle and kidney damage).
So far, the only statins significantly affected by this interaction are:
atorvastatin (Lipitor®)
lovastatin (Mevacor®)
simvastatin (Zocor®)
Other statins do not seem to demonstrate the same, profound effect with grapefruit as seen with the other statins. These would include:
rosuvastatin (Crestor®)
pravastatin (Pravachol ®)
fluvastatin (Lescol ®)
For the full article - here is the link:
http://cholesterol.about.com/od/statind ... itstat.htm
Ken.
