TheBigNewt
Well-Known Member
- Messages
- 1,167
- Type of diabetes
- Type 1
- Treatment type
- Insulin
However, in 2010 an analysis of 6801 women led by Dr Samia Mora (Brigham and Women's Hospital, Boston, MA), which included the JUPITER study, showed that statin therapy does provide a primary prevention benefit to women. In a gender-specific analysis of JUPITER , rosuvastatin (Crestor, AstraZeneca) significantly reduced the relative risk of the primary end point—a composite of MI, stroke, revascularization, hospitalization for unstable angina, and death from cardiovascular causes—by 46%. The decrease was driven by a reduction in the risk of revascularization and hospitalization for unstable angina.
So they didn't find a mortality difference, but the women needed fewer stents and had fewer hospitalizations for CAD. But there's not been a primary prevention trial just using women. And there may possibly never be one because these trials are expensive and every statin except Crestor (the most potent one) is now generic, so no drug company is gonna foot the bill. But heart disease is the leading killer of women now I think. I say if your cholesterol is pretty high you outta take one unless you're over 70 years old.
So they didn't find a mortality difference, but the women needed fewer stents and had fewer hospitalizations for CAD. But there's not been a primary prevention trial just using women. And there may possibly never be one because these trials are expensive and every statin except Crestor (the most potent one) is now generic, so no drug company is gonna foot the bill. But heart disease is the leading killer of women now I think. I say if your cholesterol is pretty high you outta take one unless you're over 70 years old.