Ian DP
Well-Known Member
Below are some clinical trials I have found on the web. If true I would have thought there should be a much stronger emphasis on keeping our sugar levels below 5.6 at 2hrs and below 7.8 after 1hr.
NHS guidance I have received are to keep sugar levels at much higher levels. After reading these clinical trials I am now testing every 1hr after meals (previously only testing before meals) and eating much less carbs in order to get under the above figures........ I am LADA, so still have some working beta cells..... And want to keep my good cells for as long as possible.
1). Beta Cell Destruction Begins at 2-hr OGTT Test Readings Over 100 mg/dl (5.6 mmol/L)....Italian research by A Gastardelli....The beta cells are the cells in the pancreas that produce the insulin your body uses to control your blood sugar.
Analyzing their data further, they found that with every small increase in the 2-hour glucose tolerance test result, there was a corresponding increase in how much beta cell failure was detectable. The higher a person's blood sugar rose within "normal" range, the more beta cells were failing.
2). Prolonged Exposure to Blood Sugars Over 140 mg/dl (7.8 mmol/L) Kills Human Beta Cells....R. Paul Robertson, one of authors of this study wrote, "I think the glucose toxic effects begin when blood glucose gets above 140 (7.8) and probably earlier."
3). One Hour OGTT Result over 155 mg/dl(8.6 mmol/L) Correlates with Markers for Cardiovascular Disease.....it is essential to keep one hour blood sugar reading after meals under 140 mg/dl (7.8mmol/L)
4). Beta Cells Die Off in People Whose Fasting Blood Sugar is Over 110 mg/dl (6.1 mmol/L)....An intriguing study shows the severe organ damage experienced by people whose blood sugar falls into a range most doctors consider to be near-normal. A team of researchers autopsied the pancreases of deceased patients who were known to have had fasting blood sugars that tested between 110 mg/dl and 125 mg/dl within two years of their deaths. The researchers found that these patients, whose blood sugar was not high enough for them to be diagnosed as diabetic, had already lost, on average, 40% of their insulin-producing beta cells.
5). Keeping Blood Sugars Below 140 mg/dl at All Times Improves Survival of Seriously ill Patients
6). Nerve Damage Occurs when Blood Sugars Rise Over 140 mg/dl (7.8 mmol/L) After Meals...neurology clinic at the University of Utah
From what I could establish, these clinical trials are not new (4 to 10 years old). But new to me and quite a shock...... Especially when I started 1hr testing, which I found were often over 10 at 1hr, but down to 5.5 before next meal.
I have now stopped eating potatoes and pasta, only eating small quantities of rice (basmati, brown where possible) and only low GI bread (whole grain) one slice max per meal, two slices max per day..... Seems to be working so far.... Time will tel how long!!!!
Ian
Sent from the Diabetes Forum App
NHS guidance I have received are to keep sugar levels at much higher levels. After reading these clinical trials I am now testing every 1hr after meals (previously only testing before meals) and eating much less carbs in order to get under the above figures........ I am LADA, so still have some working beta cells..... And want to keep my good cells for as long as possible.
1). Beta Cell Destruction Begins at 2-hr OGTT Test Readings Over 100 mg/dl (5.6 mmol/L)....Italian research by A Gastardelli....The beta cells are the cells in the pancreas that produce the insulin your body uses to control your blood sugar.
Analyzing their data further, they found that with every small increase in the 2-hour glucose tolerance test result, there was a corresponding increase in how much beta cell failure was detectable. The higher a person's blood sugar rose within "normal" range, the more beta cells were failing.
2). Prolonged Exposure to Blood Sugars Over 140 mg/dl (7.8 mmol/L) Kills Human Beta Cells....R. Paul Robertson, one of authors of this study wrote, "I think the glucose toxic effects begin when blood glucose gets above 140 (7.8) and probably earlier."
3). One Hour OGTT Result over 155 mg/dl(8.6 mmol/L) Correlates with Markers for Cardiovascular Disease.....it is essential to keep one hour blood sugar reading after meals under 140 mg/dl (7.8mmol/L)
4). Beta Cells Die Off in People Whose Fasting Blood Sugar is Over 110 mg/dl (6.1 mmol/L)....An intriguing study shows the severe organ damage experienced by people whose blood sugar falls into a range most doctors consider to be near-normal. A team of researchers autopsied the pancreases of deceased patients who were known to have had fasting blood sugars that tested between 110 mg/dl and 125 mg/dl within two years of their deaths. The researchers found that these patients, whose blood sugar was not high enough for them to be diagnosed as diabetic, had already lost, on average, 40% of their insulin-producing beta cells.
5). Keeping Blood Sugars Below 140 mg/dl at All Times Improves Survival of Seriously ill Patients
6). Nerve Damage Occurs when Blood Sugars Rise Over 140 mg/dl (7.8 mmol/L) After Meals...neurology clinic at the University of Utah
From what I could establish, these clinical trials are not new (4 to 10 years old). But new to me and quite a shock...... Especially when I started 1hr testing, which I found were often over 10 at 1hr, but down to 5.5 before next meal.
I have now stopped eating potatoes and pasta, only eating small quantities of rice (basmati, brown where possible) and only low GI bread (whole grain) one slice max per meal, two slices max per day..... Seems to be working so far.... Time will tel how long!!!!
Ian
Sent from the Diabetes Forum App
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