This is by no means an argument against your comment but comes from a need for a little more detail.
I know very little about Type 1 Diabetes but have heard/read nothing on the glucagon response, could you say a little on the mechanism whereby in the absence of insulin the glucagon response is faulty in T1, thanks.
The hormone insulin works as a hepatocyte to stimulate glycogen synthase, the release of glycogen when blood sugar is too low. The endocrine part of the pancreas, the pancreatic islets have two main functions. Alpha cells for glucagon production, and beta cells for insulin. When beta cells produce insulin it will stimulate the alpha cells to a glucagon secretion, this is not possible without insulin as a hepatocyte.
Since type 1 diabetics does not have beta cells, there isn’t any hormone (insulin) to stimulate the release of glucagon from alpha cells.
So type 1 diabetics do have alpha cells, but the mechanism is broken due to the lack of beta cells.
Emile, you are making statements that simply are not true.
None of us know whether
@derry60 had a hypo or not, because she did not test at the time.
Whether she had a hypo, or not, you should not be making absolute statements without enough information.
And you are 100% wrong that
only T1s on insulin will pass out from hypos.
Severe blackout hypos can be caused by insulinomas, RH, medications
other than insulin, and health conditions
other than diabetes. So your statement is simply wrong.
https://www.healthline.com/health/hypoglycemia#prevention
Please stop making absolute statements that give out incorrect information that may mislead members.
I do not mislead, I talk from experience, and by the information in this tread it does not seem like a hypo. Sorry if you do not agree with me, but from experience I can tell that a hypo have to be really severe before you get «memory loss» of the hypoglycemic episode. And I can also tell that OP did not have a severe hypo as she renoveres just fine without medical care.
The article you posted mentioned that hypoglycemia could occure to other conditions than diabetes, and I never denied that.
I statens that hypoglycemic coma was not possible without medications like insulin, because: the glycogen synthase are only defect in type 1 diabetics or people with an endocrine pancreas insufficiency. The glycogen synthase dumps glycogen to prevent a lethal coma.
If you had read the whole article before wronging me, you would have read that severly low hypoglycemia calls on immediate treatment. If someone states they had a hypo, but does not remember, it would mean they had a real severe hypo. And to be fair, you won’t live through a severe hypo without medical care.
I do not know if you’re diabetic, or have people close to you with diabetes. But let me just say this, if you forget or does not remember a hypo (like
op say), then it would mean you have had a severe hypo. And if you do ever have or experience a severe hypo, I can trust you that it is not just like feeling drunk, but much worse.
Also I know that me, and others wouldn’t be here without immediate help if we ever get a hypo that are so severe that we does not remember all of it.
Of course op could have had a mild hypo, but the part of her not remember what happened makes me believe it was not a hypo.
I don’t mean to make absolute statesmemt, but I think I have my right share of telling the difference from a severe hypo or not. At least I think I know more of how it feels then people who have never had to deal with this in real
Of course you can make wrongs on a forum, because I only know what op wrote and never really were there. But, from my experience and knowledge (education) it does not sound like a hypoglycemic episode to me.