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James1968

James1968

Well-Known Member
Messages
441
Type of diabetes
Type 2
Come home from work this morning and check my BS 7.5, forgot to take medication,metformin 1000mg and gliclazide 80mg, I get up and check BS and it's sitting at 7.0
I thought this would have went up with not taking medication
Thanks in advance
Sorry if this has been asked before
 
As far as I know, Gliclazide only works when you have eaten as it stimulates the pancreas to produce extra insulin to deal with the glucose produced from the food.

Metformin is a mild drug that does very little to lower blood sugars. It helps in other ways, one of which is to reduce the amount of glucose the liver produces - the liver produces glucose when we wake up and start the day. It accumulates in the body, so missing a dose will have no or little effect at all.
 
Last edited:
Yes, Metformin is a long term cumulative drug.
It isn't like a shot of insulin which knocks your BG down immediately.
 
If you are eating low carb, then the figures may well keep getting better with or without the drugs :)
So overall you seem to be doing well ! congratulations
 
https://www.drugbank.ca/drugs/DB01120
Bluetit1802 said:
As far as I know, Gliclazide only works when you have eaten as it stimulates the pancreas to produce extra insulin to deal with the glucose produced from the food.
.
Click to expand...
Gliclizide effects the pancreas to stimulate insulin production both withfood intake and without it, although I dont know the relative strength of each effect, it also effects bodily cells' insulin sensitivity And reduces gluconeogenesis by the liver
https://www.drugbank.ca/drugs/DB01120
 
badcat said:
Gliclizide effects the pancreas to stimulate insulin production both with food intake and without it, although I dont know the relative strength of each effect,
Click to expand...

When I was taking Gliclazide I managed to take it late one day, lunch time rather than breakfast, then skipped lunch because I was doing stuff in the garden. Big mistake, I had a hypo. As badcat says, insulin was being produced although I'd not eaten and as for the effect and the strength, in my case it was substantial and fairly quick.
 
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