GABA to treat type 1 diabetes after human beta cell transplantation

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The chemical gamma-aminobutryic acid (GABA) has been found to treat and even reverse type 1 diabetes after human beta cell transplantation into mice. What is GABA? GABA is an amino acid produced by the same beta cells that make and secrete insulin. It was previously found to prevent and reverse type 1 diabetes in mice. The December issue of Diabetes features a paper that shows GABA does the same thing when mice have been injected with human pancreatic cells. Known as a key neurotransmitter in the brain, the role of GABA in the pancreas was previously unknown until a 2011 paper by Drs. Prud'homme and Wang. They found that GABA greatly improved the survival rate of pancreatic cells following transplantation into mice, with type 1 diabetes characterised by the immune system's destruction of pancreatic beta cells. Human clinical trials The researchers believe this finding could result in research specifically related to pancreatic transplants, but GABA, and related therapies, would require testing in human clinical trials. This could take years, the researchers note, as well as acknowledging that work in mice does not always translate to effective therapies for humans.

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Ushthetaff

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Type of diabetes
Type 1
Treatment type
Insulin
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Mountain out of mole hill makers ,queues , crowds , shopping on a Saturday hmm just shopping I guess no matter what day it is
I’ll not hold my breath , I’ve had diabetes a over 40 years and a cure has been “ just around the corner” for most of those years , all I’ll say is the road to the “ corner “ is endless , to be honest I’m that use to diabetes now , it and all problems are all part of my life , a cure would be good but I can’t see it any time soon …. Sorry to be the killjoy