Glimepiride & Linagliptin (Tradjenta) Combination :S

Snuggs

Newbie
Messages
3
Type of diabetes
Type 2
Treatment type
Tablets (oral)
So the story.. so far i was diagnosed T2 in Mid/Late 2014 and have been on Glimepiride 4mg since and the DN had my recent Hb1Ac stating that it was higher then usual (attempting to insinuate that i haven't been in control) and as a result she has suggested (and prescribed) Linagliptin 5mg in additional to the Glimepiride as a combination therapy.

I am a firm believer in reading up on any new medication(s) and possible interactions with anything else that I am taking.. and the conclusion is that of I would be at Moderate risk on having my frequent hypo's!

So i guess the ultimate question is...What are your views/experiences on this combination?
 

Lamont D

Oracle
Messages
15,953
Type of diabetes
Reactive hypoglycemia
Treatment type
I do not have diabetes
Any meds that are gliptins such as trajenta, will help bring your blood glucose levels down. As long as you start having real control of your blood glucose levels.
You will not get hypos until you can control your blood glucose levels near normal blood glucose levels.
Then your GP will probably reduce your meds. Not until!

How to help with getting your blood glucose levels down is what kind of diet you are on.
The low carb forum is great for ideas and recipes, the success stories forum has lots of diabetics who have been where you are now, and have achieved good levels.
It is up to you.
Reduce your carbs
Reduce your plate size
Increase your exercise if you can. Just walking a bit more can really help!
You will be surprised what happens.

Keep asking questions, you will get some great answers from knowledgeable diabetics.

If you haven't already had the newbies welcome, I've tagged @daisy1 to oblige.
Some great information there.

Best wishes and welcome.
 

alison.81

Well-Known Member
Messages
49
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Hi

I am on Linagliptin and have been taking it since October last year and I have never had any problems with it. I also take Metformin with it and touch wood have not had an hypo.
 

daisy1

Legend
Messages
26,457
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Dislikes
Cruelty towards animals.
@Snuggs

Hello Snuggs and welcome to the forum :) Here is the information we give to new members and I hope you will find it useful and helps you to get better sugar levels. Ask more questions and someone will be able to help.


BASIC INFORMATION FOR NEW MEMBERS

Diabetes is the general term to describe people who have blood that is sweeter than normal. A number of different types of diabetes exist.

A diagnosis of diabetes tends to be a big shock for most of us. It’s far from the end of the world though and on this forum you’ll find over 150,000 people who are demonstrating this.

On the forum we have found that with the number of new people being diagnosed with diabetes each day, sometimes the NHS is not being able to give all the advice it would perhaps like to deliver - particularly with regards to people with type 2 diabetes.

The role of carbohydrate

Carbohydrates are a factor in diabetes because they ultimately break down into sugar (glucose) within our blood. We then need enough insulin to either convert the blood sugar into energy for our body, or to store the blood sugar as body fat.

If the amount of carbohydrate we take in is more than our body’s own (or injected) insulin can cope with, then our blood sugar will rise.

The bad news

Research indicates that raised blood sugar levels over a period of years can lead to organ damage, commonly referred to as diabetic complications.

The good news

People on the forum here have shown that there is plenty of opportunity to keep blood sugar levels from going too high. It’s a daily task but it’s within our reach and it’s well worth the effort.

Controlling your carbs

The info below is primarily aimed at people with type 2 diabetes, however, it may also be of benefit for other types of diabetes as well.
There are two approaches to controlling your carbs:

  • Reduce your carbohydrate intake
  • Choose ‘better’ carbohydrates

Reduce your carbohydrates

A large number of people on this forum have chosen to reduce the amount of carbohydrates they eat as they have found this to be an effective way of improving (lowering) their blood sugar levels.

The carbohydrates which tend to have the most pronounced effect on blood sugar levels tend to be starchy carbohydrates such as rice, pasta, bread, potatoes and similar root vegetables, flour based products (pastry, cakes, biscuits, battered food etc) and certain fruits.

Choosing better carbohydrates

Another option is to replace ‘white carbohydrates’ (such as white bread, white rice, white flour etc) with whole grain varieties. The idea behind having whole grain varieties is that the carbohydrates get broken down slower than the white varieties –and these are said to have a lower glycaemic index.
http://www.diabetes.co.uk/food/diabetes-and-whole-grains.html

The low glycaemic index diet is often favoured by healthcare professionals but some people with diabetes find that low GI does not help their blood sugar enough and may wish to cut out these foods altogether.

Read more on carbohydrates and diabetes

LOW CARB PROGRAM:
http://www.diabetes.co.uk/low carb program


Eating what works for you

Different people respond differently to different types of food. What works for one person may not work so well for another. The best way to see which foods are working for you is to test your blood sugar with a glucose meter.

To be able to see what effect a particular type of food or meal has on your blood sugar is to do a test before the meal and then test after the meal. A test 2 hours after the meal gives a good idea of how your body has reacted to the meal.

The blood sugar ranges recommended by NICE are as follows:

Blood glucose ranges for type 2 diabetes
  • Before meals: 4 to 7 mmol/l
  • 2 hours after meals: under 8.5 mmol/l
Blood glucose ranges for type 1 diabetes (adults)
  • Before meals: 4 to 7 mmol/l
  • 2 hours after meals: under 9 mmol/l
Blood glucose ranges for type 1 diabetes (children)
  • Before meals: 4 to 8 mmol/l
  • 2 hours after meals: under 10 mmol/l
However, those that are able to, may wish to keep blood sugar levels below the NICE after meal targets.

Access to blood glucose test strips

The NICE guidelines suggest that people newly diagnosed with type 2 diabetes should be offered:

  • structured education to every person and/or their carer at and around the time of diagnosis, with annual reinforcement and review
  • self-monitoring of plasma glucose to a person newly diagnosed with type 2 diabetes only as an integral part of his or her self-management education

Therefore both structured education and self-monitoring of blood glucose should be offered to people with type 2 diabetes. Read more on getting access to bloodglucose testing supplies.

You may also be interested to read questions to ask at a diabetic clinic

Note: This post has been edited from Sue/Ken's post to include up to date information.
 

kokhongw

Well-Known Member
Messages
2,394
Type of diabetes
I reversed my Type 2
Treatment type
Diet only
The function of these medication is to increase our insulin secretion or inhibit glucagon production in order to better handle excessive carbs intake. Often it can become a vicious cycle of taking more carbs to prevent hypo...and having constantly elevated glucose level.

Do keep in mind that T2D is a condition of both elevated insulin AND glucose level. Medication focus only on treating the elevated glucose level, not the elevated insulin level.