From experience (sadly) if you have experienced any unexplained bruising ( we are talking big bruises not little ones) muscle or joint pain, or pain in your lower back (kidneys), see a doctor as quick as you can and tell them about the grapefruit. i suffered this while on high dose simvastatin without the grapefruit and had to drop the dose then change to lipitor, but caught it early enough to avoid any lasting damage. If I hadn't know about the grapefruit it would have been much worse.
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