Hiya - Any advice?

Sitagliptin increases your insulin levels on your first phase insulin response because of insulin resistance, or intolerance to certain foods.
Your body is used to high levels and will want to keep you there. But will only cause more long term damage because of hyperglycaemia.
Getting down towards normal blood glucose levels will be beneficial. The need for going back to low carb is recommended.
Take care with your exercise, as too much may cause liver dumps, which do not help if your first phase insulin response is not good.
Best wishes

Sorry for butting in but what is LADA?

Vyleros said:

Hey!

So Jan 2022 I was told my HBA1C was down to 34. I can't remember the numbers it dropped to before it reached 34 but had no tests since until Monday just gone when it was 102. They used the word "reversed" so I just assumed that's what I had done

Last 12 months or so my mental health has been really bad (C-PTSD, anxiety etc) and my diet hasn't been good just due to lack of care.

Still waiting for diabetic review as GP today said it maybe something called LADA but she said I'd have to wait for my review to see what it is.

Appreciate your reply and thanks for the information.

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Totally understand where you are coming from regarding the mental health, its a constant battle at the best of times. You will get there though and the fact your hba1c was down to 34 proves that you can do it again

LADA Latent autoimmune disease in adults is type 1. LADA is a term used to describe getting it as an adult because it is usually slow progression versus a faster progression when you are younger. LADA/type 1 is a slower loss of insulin productions and sometimes diet and lifestyle changes will work for a while....... until it doesn't. You have what you call a honeymoon period when you still make some insulin and it can vary day to day. It can also last up to 8 years plus.

Two tests help to diagnose it. An antibody test, which if positive is a sign you are a type 1. But some people test negative and still don't make insulin and they don't know why. Plus, commonly only a GAD test is done because of costs and because it is the most likely antibody found. But it is not the only antibody test. The second test is a C-Peptide test. If low or low normal it's a sign of being a type 1 as you are not making insulin or enough insulin. High or high normal is a sign of type 2 as you are making insulin, usually a higher amount trying to make up for being insulin resistant.

A lot of LADA/type 1's need insulin within 3 years. There is some theory that taking insulin early might help save your insulin production a little longer. Taking some meds might speed up the process. I always say if things don't make sense you might be a type 1.

In your case you have said you thought your type 2 was gone and hadn't been paying attention to your "type 2". That could easily also explain your high numbers. It's a metabolic disease that runs in families and while diet, exercise can help control it, reverting back to the old habits when you developed it would certainly bring back poor blood sugars again. However if you had high Ketones, that is very much a type 1 thing. Type 2's make insulin, they just don't use it well. But because they still make insulin they are unlikely to develop DKA. Although I think certain medications might be able to cause it in type 2's. There is something that type 2's can get, but it is rarer although more serious and I don't believe cause high ketones.

I’m not saying you are a type 1, I have no idea.

• C-Peptide
  While most tests check for antibodies, this test measures how much C-peptide is in a person’s blood. Peptide levels typically mirror insulin levels in the body. Low levels of C-peptide and insulin can point to T1D
• Glutamic Acid Decarboxylase Autoantibodies (GADA or Anti-GAD)
  This test looks for antibodies built against a specific enzyme in the insulin-producing pancreatic beta cells.
• Insulin Autoantibodies (IAA)
  This tests looks for the antibodies targeting insulin.
• Insulinoma-Associated-2 Autoantibodies (IA-2A)
  This test looks for antibodies mounted against a specific enzyme in beta cells. Both the IA-2A and GADA tests are common T1D antibody tests.
• Zinc Transporter 8 (ZnT8Ab)
  This test looks at antibodies targeting an enzyme that is specific to beta cells.
• Islet Cell Cytoplasmic Autoantibodies (ICA)
  Islet cells are clusters of cells in the pancreas that produce hormones, including insulin. This test identifies a type of islet cell antibodies present in up to 80 percent of people with T1D

And for those that are not aware of Hyperosmolar Hyperglycemic Syndrome in type 2's. It's good to be aware of it.

Vyleros said:

Hey!

So Jan 2022 I was told my HBA1C was down to 34. I can't remember the numbers it dropped to before it reached 34 but had no tests since until Monday just gone when it was 102. They used the word "reversed" so I just assumed that's what I had done

Last 12 months or so my mental health has been really bad (C-PTSD, anxiety etc) and my diet hasn't been good just due to lack of care.

Still waiting for diabetic review as GP today said it maybe something called LADA but she said I'd have to wait for my review to see what it is.

Appreciate your reply and thanks for the information.

Click to expand...

Like the warrior part, lack of care don’t get it, good luck and take care of yourself.