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How can I get my blood sugars level in the evening without having them creep up
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<blockquote data-quote="evilclive" data-source="post: 1982194" data-attributes="member: 488171"><p>Three times the concentration : but if you take eg 10u Toujeo, it's got the same amount of insulin glargine in it as 10u of Lantus.</p><p></p><p>When considering the concentration of these insulins, if you're using pens the best approach is the simple one, which is just use the U number on the pen and don't worry about the concentration. If you want to think about the concentration, remember the pens dial a different number of U per volume (or different volume per U) to compensate for it - Toujeo only comes in its own special pens.</p><p></p><p>Now, the clinical effect of Toujeo is a bit different because the way the more concentrated insulin reacts with your body is slightly different - the smaller volume makes a difference. I think insulin glargine works by crystallising out at body pH then very slowly dissolving, and a more concentrated solution could well give bigger crystals and hence a slower release. So it's ok to have a different body reaction to it.</p><p></p><p>I used Lantus for several years, but it wasn't working great for me. I tried Toujeo and didn't like it because its peak was at the wrong time for me. Now on Levemir 2 doses, which seems to be behaving fairly well. But what works for me might well be the wrong approach for others.</p><p></p><p>And my fun U fact, mentioned a couple of months ago : a U of insulin is the amount required to put a rabbit into a hypo.</p></blockquote><p></p>
[QUOTE="evilclive, post: 1982194, member: 488171"] Three times the concentration : but if you take eg 10u Toujeo, it's got the same amount of insulin glargine in it as 10u of Lantus. When considering the concentration of these insulins, if you're using pens the best approach is the simple one, which is just use the U number on the pen and don't worry about the concentration. If you want to think about the concentration, remember the pens dial a different number of U per volume (or different volume per U) to compensate for it - Toujeo only comes in its own special pens. Now, the clinical effect of Toujeo is a bit different because the way the more concentrated insulin reacts with your body is slightly different - the smaller volume makes a difference. I think insulin glargine works by crystallising out at body pH then very slowly dissolving, and a more concentrated solution could well give bigger crystals and hence a slower release. So it's ok to have a different body reaction to it. I used Lantus for several years, but it wasn't working great for me. I tried Toujeo and didn't like it because its peak was at the wrong time for me. Now on Levemir 2 doses, which seems to be behaving fairly well. But what works for me might well be the wrong approach for others. And my fun U fact, mentioned a couple of months ago : a U of insulin is the amount required to put a rabbit into a hypo. [/QUOTE]
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How can I get my blood sugars level in the evening without having them creep up
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