I dont know a lot about insulin but I recall when I was first diagnosed when a junior doctor on the hospital diabetes team ( I was an inpatient at the time) came to me and said
“ Im going to prescribe insulin and needles for you and youll be injecting for the rest of your life, but youll need to watch out otherwise you’ll end up the size of a house”
Luckily I didnt end up on insulin as I questioned why diet or oral meds werent the first thing to try? She replied “ dont be stupid, those will never work, youre far too young, you’re only in your 20’s” - when I pointed out that I was actually going to be 40 at my next birthday she said “0h, are you sure.?” Looked at my medical notes and said “ oh thats right, Ill prescribe Gliclizide instead and review how youre getting on in a week” - never saw her again
Anyway tales of medical **** ups and how I avoided insulin aside, that conversation has always made me wonder where cause and effect lie in situations of v high weight and v high insulin doses