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Insulin resistance

Antje77 said:
Sounds right to me. But you proceeded to state that most/all T1's tend to be underweight. Therefore my reaction, nothing to do with your statements about T2 :)
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Would a T1 who is not yet on insulin be over-weight unless they were also insulin resistant?
 
Antje77 said:
I never thought you were arguing! We're all on this forum to learn :) (and share, and moan, and celebrate as well of course)
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IMO quite a lot of people are on this forum to argue, though of course not exclusively for that. Just saying (not arguing, well would I?)
 
To get back to the OP, I do not think it is a matter of 'quality' of insulin but quantity of insulin.

In the case of T2 insulin resistance causes a need for higher levels of insulin, this higher level of insulin itself promotes more insulin resistance. It is a vicious circle. The big question remains unanswered, what is the root cause/s of insulin resistance?
 
Ok to add more confusion.

I thought T2 began by overproducing insulin in an effort to compensate for insulin resistance. Ie an inability to use the insulin normally. Eventually this overproduction leads to a burn out situation whereby the pancreas gives up producing insulin necessitating injected artificial insulin in the same way as T1. Between these stages a type 2 can use insulin injections to further boost their natural insulin in a medical attempt to overcome the resistance. Insulin stores glucose as fat and lots of insulin means lots of fat stored, hence many T2 being overweight.

My question would be what actually reverses the resistance ie makes better or more receptors. Because if you can reduce/eliminate resistance then no need for ever increasing insulin levels as a little will then go a low way (in dealing with glucose and carbs) so to speak. This is different to reducing the demand for insulin by reducing glucose (ie carbs) which to me is management not cure. I’ve read that exercise and weight loss actually CREATES more receptors and improves functionality of existing receptors. Does anything else do this as a permanent improvement? - I think some of the commonly used medications Improve function but presumably if they are withdrawn you’re back to square one without other intervention.
 
Is there anyone here with what alexandra100 quotes as "double diabetes", i.e, having type 2 symptoms, when youre a type 1, and is there an actual diagnosis term for it? I was thinking about this earliar. If I become insulin resistant when im older to the point where insulin is ineffective, then what happens? Or does this not happen as extreme as what im making out
 
Dixon1995 said:
Is there anyone here with what alexandra100 quotes as "double diabetes", i.e, having type 2 symptoms, when youre a type 1, and is there an actual diagnosis term for it? I was thinking about this earliar. If I become insulin resistant when im older to the point where insulin is ineffective, then what happens? Or does this not happen as extreme as what im making out
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I probably have T1 and I'm fat as well, so a likely candidate. How do you prove insulin resistance? I've read quite alot about how much insulin T2's, T1's and LADA's use and can't find much consistency, so amount of insulin needed doesn't seem diagnostic of IR. Possibly with the exeption of people needing hundreds of units a day.
 
It’s just called having insulin resistance. I don’t like using the term ‘double diabetes’ or having ‘type 1 and type 2’. It doesn’t help with the educating about type 1 and type 2 being two different conditions. Also as a type 1 I can’t have type 2 ever. My pancreas cannot start producing insulin again.
 
Antje77 said:
I probably have T1 and I'm fat as well, so a likely candidate. How do you prove insulin resistance? I've read quite alot about how much insulin T2's, T1's and LADA's use and can't find much consistency, so amount of insulin needed doesn't seem diagnostic of IR. Possibly with the exeption of people needing hundreds of units a day.
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Im sure I seen a member posting the other day about how they became insulin resistant and were taken off insulin because it wasn't working(Type 2) im not really clued up on it to be honest to give an informed opinion on it, but I was just wondering if there's anyone who rejects artificial insulin? Is that insulin resistance too

@Emily95 Hello, that's fair enough, thanks for clearing that up. Yeah I get that, I was just confused as to wht Alexandra100 meant by it.
 
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Antje77 said:
I probably have T1 and I'm fat as well, so a likely candidate. How do you prove insulin resistance? I've read quite alot about how much insulin T2's, T1's and LADA's use and can't find much consistency, so amount of insulin needed doesn't seem diagnostic of IR. Possibly with the exeption of people needing hundreds of units a day.
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There is Dr. Joseph Kraft's five hour insulin assay but no one uses this. Catherine Croft, who is using extensive data by Kraft is working on a two hour assay - a work in progress. This assay seems to measure insulin resistance.
 
Guzzler said:
To get back to the OP, I do not think it is a matter of 'quality' of insulin but quantity of insulin.

In the case of T2 insulin resistance causes a need for higher levels of insulin, this higher level of insulin itself promotes more insulin resistance. It is a vicious circle. The big question remains unanswered, what is the root cause/s of insulin resistance?
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I 100% agree with this. The more insulin there is floating round the body the more resistant our cells will become to it, and the more resistant our cells become the more insulin we neeed. Vicious circle.
 
Bluetit1802 said:
I 100% agree with this. The more insulin there is floating round the body the more resistant our cells will become to it, and the more resistant our cells become the more insulin we neeed. Vicious circle.
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Hi
First I want to thank all members for their constructive participation
you would like to say that the problem is accumulating
 
HICHAM_T2 said:
Hi
First I want to thank all members for their constructive participation
you would like to say that the problem is accumulating
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Spiraling describes it well.
 
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Guzzler said:
Spiraling describes it well.
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So why does not a diabetic become like other people when he controls the level of blood sugar When A1C it returns under 5.4% like every body can eat anythings
 
HICHAM_T2 said:
So why does not a diabetic become like other people when he controls the level of blood sugar When A1C it returns under 5.4% like every body can eat anythings
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Because the root cause has not been fixed. There are people who regain some insulin sensitivity but even they must admit that to return to their former 'normal' diet would see their blood glucose levels compromised.
There is no cure but there can be excellent management.
 
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