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Interesting scientific developments in T2 treatment

After an amount of reading, it does seem to be a good subject for further study, as to how it turns the switch on and off.
I can't find any drugs company who have the 'drug' in any development stage, it seems to be pure research at the moment, although there does seem to be one private research company looking at a possible market for it for cardiovascular issues.
 
SunnyExpat said:
I can't even begin to see where you get 'arsenic' from.
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Okay. I never said they WERE feeding them arsenic.

Also. 60% fat means WHAT in carbs and protein. STILL don't have enough information to responsibly report that the FAT made them obese. I eat <5% carbs, =/<20% protein, and =/>75% fats... I am dropping weight like there is no tomorrow. 40lbs in 3 months to be exact. So in other words, I am becoming UNobese. So, to make mice obese using "high fat" means there HAS to be more to the story. What were the carb percentages? If 30% (for example) are grain based carbs with fructose/glucose added, well then, my Friend, this is irresponsible reporting. Do you understand yet? The arsenic ANALOGYrepresents what is NOT being disclosed in the report.
 
Myangelsmom said:
Okay. I never said they WERE feeding them arsenic.

Also. 60% fat means WHAT in carbs and protein. STILL don't have enough information to responsibly report that the FAT made them obese. I eat <5% carbs, =/<20% protein, and =/>75% fats... I am dropping weight like there is no tomorrow. 40lbs in 3 months to be exact. So in other words, I am becoming UNobese. So, to make mice obese using "high fat" means there HAS to be more to the story. What were the carb percentages? If 30% (for example) are grain based carbs with fructose/glucose added, well then, my Friend, this is irresponsible reporting. Do you understand yet? The arsenic ANALOGYrepresents what is NOT being disclosed in the report.
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I understand, but to be honest, I don't care if they inflated them up with a balloon pump.
But I do care about the FGF1 results after the inflation.
I'm really not precious about LCHF.
 
bearMedicine said:
I only mentioned them because the abstract that you referred to did:
"The new study suggests that in mice, as in people, genetic susceptibility to type 2 diabetes and other metabolic problems may only become apparent when on an unhealthy diet, particularly one that leads to obesity."

My point is that we still don't really understand what kind of diet leads to obesity and general ill health, as described in the abstract with respect to mice. The abstract also speaks of changing the mice to a "healthy" diet i.e. one which is lower in fat. This presumes that a low-fat diet is healthy, which is in dispute. It's not about labels for me either, but the study you referenced decided to use them.
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It may be healthier for mice. The corolllary is not necessarily true, as you just pointed out. i have problems with these studies that show significant effects using animal subjects. where they are subjected to very abnormal loads to prove a point. Some researchers go to great lengths to match their test subjects to a trial, not because they represent the best hunan analog but for some other unspecified reason, and I find myself asking why did they choose <<say, albino South African tree frogs>> for this or that. In some studies I have seen the test subjects were already challenged by a pre existing condition that may well have skewed the test results (i.e. naturally obese/ dwarf / vegans to be force fed animal fat to see if their livers explode)

Edit to clarify: my comments wrt animal subjects refers to previous experimental studies, not the one being discussed here
 
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SunnyExpat said:
After an amount of reading, it does seem to be a good subject for further study, as to how it turns the switch on and off.
I can't find any drugs company who have the 'drug' in any development stage, it seems to be pure research at the moment, although there does seem to be one private research company looking at a possible market for it for cardiovascular issues.
Click to expand...

Yes it does kind of completely turn around our understanding of T2D. That the problem lies with the neural network.

I wonder what they discovered about the beta cells of the mice that were injected with the 10% strength FGF1 to the brian. Did they suddenly come alive with first phase response or simply that all cells becomes highly sensitize to insulin. Intriguing.
 
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