I use the Fastclix and started with a setting around 2 to 2.5. Try lower or higher settings until you get a drop of blood and the prick feels comfortable.
It's possible, if you choose to do so, to use the lancets more than once but you may find they will probably get blunt with re-use and need a higher setting - at which time you usually need to change to the next. N.B. Some people are happy to re-use the lancets, others are noit.
Check the manual as sometimes you need an adapter if you use a site other than your finger. Don't be tempted to test different fingers at the same time, as your blood's circulating, and your glucose levels are constantly changing due to this - so you're usually unlikely to get the same results. Do one test at a time and look for trends and patterns instead - your meter can be set up to record results.
Robbity