Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Guest, the forum is undergoing some upgrades and so the usual themes will be unavailable for a few days. In the meantime, you can use the forum like normal. We'd love to know what you think about the forum! Take the 2025 Survey »
Was diagnosed as type 2 in 2019. Well controlled with low carb. Two years ago was told l have Old Dominion/ Burton upon Trent sub type. Can’t get much info on it,anyone help? 3 brothers have same.
I think this isn't actually a variety of Type 2 diabetes, but relates to a rare haemoglobin type. It seems to be commoner in people with Scots-Irish ancestry. Where it relates to Type 2 diabetes is that it can affect HbA1c results - so that Hba1c values are "spuriously" inflated. There are a number of factors and conditions that can mean the HbA1c test is not reliable for T2 diagnosis, and this is one of them.
A hitherto unrecognized hemoglobin variant, encountered in four unrelated persons of Irish or Scots-Irish ancestry, hemoglobin Old Dominion/Burton-upon-Trent, beta 143 (H21) His-->Tyr, has now been characterized at the molecular, structural, and functional levels. Although it is associated with a …