Low thyroid (T3) hormone

caroline_92

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Messages
153
Type of diabetes
Treatment type
Diet only
Hi and does anyone have any insight or knowledge about thyroid hormones? I did a blood test to check out my levels, more for an experiment that anything else, and it has come back slightly low on T3 (2.57 vs 'normal' of 3.1).
T4, TSH and thyroid antibodies all well into normal range. As was VitD, B12, folate, iron and CRP. I eat bloomin' well and have been low carb with T2D in remission for 11 years now
1f600.png

Thyroid is really not something I know much about so wondering if I should be doing something different as a result of this test or just not worrying about it? I am so cynical of anything medical billed as 'normal' these days...
All thoughts or links to relevant and reputable articles about thyroid health especially on a low carb diet would be really appreciated. Thx!
 
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AndBreathe

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Hi and does anyone have any insight or knowledge about thyroid hormones? I did a blood test to check out my levels, more for an experiment that anything else, and it has come back slightly low on T3 (2.57 vs 'normal' of 3.1).
T4, TSH and thyroid antibodies all well into normal range. As was VitD, B12, folate, iron and CRP. I eat bloomin' well and have been low carb with T2D in remission for 11 years now
1f600.png

Thyroid is really not something I know much about so wondering if I should be doing something different as a result of this test or just not worrying about it? I am so cynical of anything medical billed as 'normal' these days...
All thoughts or links to relevant and reputable articles about thyroid health especially on a low carb diet would be really appreciated. Thx!

Caroline, I live with a thyroid condition which requires day to day treatment, and have built up some knowledge over time.
Can I ask why you had the test done? Were/Are you symptomatic? Was your test carried out in an NHS lab, or privately. If privately, did you send your test in the post? If so, was it during the ultra hot period?

If you are already diagnosed with a thyroid condition, please say what treatment you take for it.

I'm not suggesting for a nano-second that I disbelieve your results, it's just they are a of the less common, but not rare sort

Would you mind posting your thyroid hormone levels - irrespective of your "in range". Please also post the assay ranges the lab use to classify normality or otherwise.

(Sorry. Nobody expects the Spanish Inquisition! )
 

caroline_92

Well-Known Member
Messages
153
Type of diabetes
Treatment type
Diet only
Caroline, I live with a thyroid condition which requires day to day treatment, and have built up some knowledge over time.
Can I ask why you had the test done? Were/Are you symptomatic? Was your test carried out in an NHS lab, or privately. If privately, did you send your test in the post? If so, was it during the ultra hot period?

If you are already diagnosed with a thyroid condition, please say what treatment you take for it.

I'm not suggesting for a nano-second that I disbelieve your results, it's just they are a of the less common, but not rare sort

Would you mind posting your thyroid hormone levels - irrespective of your "in range". Please also post the assay ranges the lab use to classify normality or otherwise.

(Sorry. Nobody expects the Spanish Inquisition! )
Hi and thanks for your reply. I got the test done privately with medichecks as I have a couple of (mild) symptoms I thought could be related to my thyroid. And was actually just interested as a part time health coach! I have never had any diagnosis of thyroid problems, but then never had any tests before.
And yes the blood test, done by a nurse in superdrug, was done in that baking hot weather. What difference could this make?
And your Spanish Inquisition comment made me laugh - not heard that for a looong time!
 

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AndBreathe

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Hi and thanks for your reply. I got the test done privately with medichecks as I have a couple of (mild) symptoms I thought could be related to my thyroid. And was actually just interested as a part time health coach! I have never had any diagnosis of thyroid problems, but then never had any tests before.
And yes the blood test, done by a nurse in superdrug, was done in that baking hot weather. What difference could this make?
And your Spanish Inquisition comment made me laugh - not heard that for a looong time!

The reason I ask about the weather is "storage"/transit is very hot conditions can impact the quality of the sample, but we're talking small chances. Sometimes I think I just like asking questions. :)

What sort of symptoms do you have? The thing about thyroid disorders is that the symptoms are very common and also fit a wide range of other conditions, but some are more pointed than others.

What was your antibody result?

Bottom line is if you had your thyroid tested via your GP, you would simply not have got these results. With no diagnosis of thyroid disease, the NHS test TSH. If that is in range they look no further.

If TSH is abnormally high, they'll look at FT4 *Free Thyroxine). If that is normal they stop, and will sometimes even stop testing there if it is abnormal. It's not great.

Your T3 is low, which isn't great, so it could be your body isn't great at converting T4 to T3.

The way thyroid function works is TSH is released by the pituitary gland, to tell the thyroid it needs to do something. From that, you can tell, TSH isn't a thyroid hormone. If your thyroid is able to (and yours works), it responds by producing T4. T4 is a passive hormone, which is important but doesn't actually do much. Your body then has to convert it to T3, which is where the magic happens.

With low T3 you may, or may not have symptoms. It could be that your body isn't converting T4>T3 efficiently, but there are some papers out there which suggests those living a low carb lifestyle tend to have lower T3 the usually found.

In order to get any kind of diagnosis, it is usually necessary to have at least two abnormal results, and those would usually be a couple of months apart.

To get the most consistent results, the thyroid gurus recommend testing as early as possible in the morning, fasted, because thyroid function is dynamic throughout the day.

If you want to follow this up, then make an appointment with your GP. Our thyroids are a cornerstone of our metabolic health, so it is important they function as well as possible.

In your shoes, if I felt OK, I might be inclined to repeat the test in a few months, as described above.

Working out what is going on with your thyroid can be a frustratingly slow process.

If you want to dig a bit deeper into all things thyroid, I suggest the Thyroid UK area of Health Unlocked. There are some supremely knowledgeable folks on there:

 
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caroline_92

Well-Known Member
Messages
153
Type of diabetes
Treatment type
Diet only
Thank you again @AndBreathe, really appreciate you taking the time to reply.
So the fact that all my other blood results were normal and as expected leads me to assume that the weather temperature on the day didn't really affect the blood results. It was done first thing in the morning and popped straight into a priority postbox. I wasn't fasted however, as didn't know this was a good thing to do. But I probably didn't eat much for breakfast - most likely some greek yoghurt and decaf black tea which is my usual breakfast.

I can see the symptoms of thyroid problems are wide ranging, common and some overlap with the menopause. But I have been dealing with the menopause these last few years and on HRT, so think I can distinguish these

The symptoms I thought may be related to low thyroid function are feeling cold, especially hands and feet, the occasional swollen ankles (usually in the heat or after sitting at my desk all day), slow to get going in the morning (but always had this tendency!), puffy eyes sometimes, mild/occasional constipation despite eating healthy and drinking lot's. And then I have had persistent dry eyes, itchy eyes and inflammation for a few years which I have self diagnosed as hayfever/rhinitis but am trying to get to the bottom of. Potentially related to my oestrogen levels. Which thyroid symptoms are the pointy ones would you say?

The antibody results were really low: thyroglobulin <13 IU/mL and thyroid peroxidase <9 IU/mL. I have no other autoimmune conditions or symptoms at all but was interested to do this specific test (not the GP/NHS ones) to see these results. And yes, I know this is different to what is done routinely by GPs but think we should do more widespread T3 and antibody tests and my understanding is that GPs may not act until the thyroid function has deteriorated to a large and damaged extent. We know from T2D that the NHS don't have the time, funds or incentives to do anything preventative...

It is the potential issue converting T4 to T3 I am interesting in exploring and did wonder if my low carb lifestyle was affecting things. And how they have arrived at the 'normal' T3 levels interests me? Is it one of those quite arbitrary numbers based on a population of pretty unhealthy people with a pharma agenda to get more thyroid medications prescribed? I will do some digging on the Health Unlocked site - thank you for this link and I may repeat the test again.
 

AndBreathe

Master
Retired Moderator
Messages
11,581
Type of diabetes
I reversed my Type 2
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Thank you again @AndBreathe, really appreciate you taking the time to reply.
So the fact that all my other blood results were normal and as expected leads me to assume that the weather temperature on the day didn't really affect the blood results. It was done first thing in the morning and popped straight into a priority postbox. I wasn't fasted however, as didn't know this was a good thing to do. But I probably didn't eat much for breakfast - most likely some greek yoghurt and decaf black tea which is my usual breakfast.

I can see the symptoms of thyroid problems are wide ranging, common and some overlap with the menopause. But I have been dealing with the menopause these last few years and on HRT, so think I can distinguish these

The symptoms I thought may be related to low thyroid function are feeling cold, especially hands and feet, the occasional swollen ankles (usually in the heat or after sitting at my desk all day), slow to get going in the morning (but always had this tendency!), puffy eyes sometimes, mild/occasional constipation despite eating healthy and drinking lot's. And then I have had persistent dry eyes, itchy eyes and inflammation for a few years which I have self diagnosed as hayfever/rhinitis but am trying to get to the bottom of. Potentially related to my oestrogen levels. Which thyroid symptoms are the pointy ones would you say?

The antibody results were really low: thyroglobulin <13 IU/mL and thyroid peroxidase <9 IU/mL. I have no other autoimmune conditions or symptoms at all but was interested to do this specific test (not the GP/NHS ones) to see these results. And yes, I know this is different to what is done routinely by GPs but think we should do more widespread T3 and antibody tests and my understanding is that GPs may not act until the thyroid function has deteriorated to a large and damaged extent. We know from T2D that the NHS don't have the time, funds or incentives to do anything preventative...

It is the potential issue converting T4 to T3 I am interesting in exploring and did wonder if my low carb lifestyle was affecting things. And how they have arrived at the 'normal' T3 levels interests me? Is it one of those quite arbitrary numbers based on a population of pretty unhealthy people with a pharma agenda to get more thyroid medications prescribed? I will do some digging on the Health Unlocked site - thank you for this link and I may repeat the test again.
My major, major thyroid symptom was sensitivity to cold, but for me that meant being cold in 35c heat. Cold to my core, but that was quite extreme.

symptoms are individual, but the most common are weight gain/ inability to lose, shedding hair and brain fog. I had None of those.

I see an Endo for my thyroid problems, and he is very happy for me to be low carb, and he Further instructed a gluten-free lifestyle, but that is due to a plethora of AI conditions in my family.

in your shoes I would repeat the test in a couple of months and see what that returns. In the meantime please ensure your Vitamin D is towards the upper end of “normal”. Low vitamin D can impact thyroid function significantly.
 

caroline_92

Well-Known Member
Messages
153
Type of diabetes
Treatment type
Diet only
Thank you and interesting to hear about your experiences. My feeling the cold symptoms sounds very minor in comparison! And in part I feel the cold more after losing my excess weight when I went low carb
Are there any good books on thyroid health you can suggest? To help me understand more about thyroid function and ways to boost it, beyond medicating?
Thanks again for your input!
 

AndBreathe

Master
Retired Moderator
Messages
11,581
Type of diabetes
I reversed my Type 2
Treatment type
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Thank you and interesting to hear about your experiences. My feeling the cold symptoms sounds very minor in comparison! And in part I feel the cold more after losing my excess weight when I went low carb
Are there any good books on thyroid health you can suggest? To help me understand more about thyroid function and ways to boost it, beyond medicating?
Thanks again for your input!

To be honest, your results are pretty atypical, so some of the usual reading could be very disconnected to where you have found yourself.

My suggestions would be that you really optimise your vitamins and minerals - D and Bs and focus on nutritionally dense foods, that part at least you are likely doing anyway. Consider joining the Health Unlocked forum, and if you feel comfortable replicate your OP there. There are many, many with wider, deeper knowledge than I have. My issues and experiences have influenced my reading and research, so my breadth of knowledge may hinder you getting to any root cause.

But, to reiterate, with the bloods you have now, I would expect even a private Endo to want retesting, due to the dynamic nature of thyroid (and most other) hormones. A single test can be a bit like a single finger prick for blood glucose.

I'm sorry that's not ore helpful, but I don't want to unwittingly become a hindrance in you understanding your puzzle.