1. Get the Diabetes Forum App for your phone - available on iOS and Android.
    Dismiss Notice
  2. Guest, we'd love to know what you think about the forum! Take the Diabetes Forum Survey 2021 »
    Dismiss Notice
  3. Diabetes Forum should not be used in an emergency and does not replace your healthcare professional relationship. Posts can be seen by the public.
    Dismiss Notice
  4. Guest, stay home, stay safe, save the NHS. Stay up to date with information about keeping yourself and people around you safe here and GOV.UK: Coronavirus (COVID-19). Think you have symptoms? NHS 111 service is available here.
    Dismiss Notice
Dismiss Notice
Find support, ask questions and share your experiences. Join the community »

Metformin and cognitive ability

Discussion in 'Diabetes Medication and Drugs' started by Andydragon, Dec 7, 2020.

  1. Andydragon

    Andydragon Type 2 (in remission!) · Moderator
    Staff Member

    Messages:
    2,719
    Likes Received:
    3,592
    Trophy Points:
    198
    I have moments where my brain just “stops” and I lose my train of thought or the words I am looking for

    I put it down to getting older but it got me wondering, does metformin have any side effects on the brain? I’m on 2000mg daily now.

    I am taking a multi vitamin to help any B12 issues
     
  2. Resurgam

    Resurgam Type 2 (in remission!) · Expert

    Messages:
    8,948
    Likes Received:
    5,362
    Trophy Points:
    198
    Any statins? I was just describing what Atorvastatin did - at least, I assumed it was Atorvastatin. I was taking Metformin alongside it.
     
    • Informative Informative x 1
  3. Andydragon

    Andydragon Type 2 (in remission!) · Moderator
    Staff Member

    Messages:
    2,719
    Likes Received:
    3,592
    Trophy Points:
    198
    No, only drugs I am now on are metformin, vitamin C and centrum multivitamin
     
  4. A_Sun

    A_Sun Type 2 · Member

    Messages:
    23
    Likes Received:
    34
    Trophy Points:
    33
    Oh yes me too. Do you think it could be the metformin?
     
  5. Andydragon

    Andydragon Type 2 (in remission!) · Moderator
    Staff Member

    Messages:
    2,719
    Likes Received:
    3,592
    Trophy Points:
    198
    I don’t have metformin anymore and still have this so have just put it down to age unfortunately. I couldn’t find any known links to anything
     
  6. ziggy_w

    ziggy_w Type 2 · Well-Known Member

    Messages:
    3,021
    Likes Received:
    8,605
    Trophy Points:
    198
    Hi @Andydragon,

    Have you actually been checked for Vit B/Vit B12 deficiency? For some, metformin can be associated with problems in Vit B12 uptake (from foods and vitamins taken orally) and one of the symptoms can be cognitive issues. It might be worthwhile getting it tested anyway.

    Usually, if these types of cases, B12 injections are prescribed.
     
  7. Erin

    Erin Type 2 · Well-Known Member

    Messages:
    569
    Likes Received:
    143
    Trophy Points:
    103
    I doubt it, because so many things can cause transient or continued cognitive difficulties; sometimes just switching dose or drug. And btw, I have changed my mind about stopping metformin as the major adverse effect (lactic acidosis) is very rare, and the benefits as described on this Website today are far greater than the risks. Sometimes, it is the weight put on an adverse effect that makes people anxious about a drug. That's why it's good to read the manufacturer's blurbs.
     
  8. zand

    zand Type 2 · Master

    Messages:
    10,282
    Likes Received:
    16,220
    Trophy Points:
    298
    I recently found out that back in 2008 ( I was diagnosed T2 in 2011) I was very slightly deficient in B12. I restarted metformin in February and am now B12 deficient. I guess some of us just don't absorb it properly and taking metformin can make this worse.

    My brain just stops too. Having Covid19 was the beginning of this, but now with B12 deficiency added it's much worse. It's taken me several minutes to type this post and I am still not sure whether it is coherent or not.
     
  9. Resurgam

    Resurgam Type 2 (in remission!) · Expert

    Messages:
    8,948
    Likes Received:
    5,362
    Trophy Points:
    198
    It is some years since I stopped the Metformin and Atorvastatin, and I did improve in ability to remember - but not entirely.
    After getting the first AZ jab earlier this year my feet and lower legs were very swollen and so - after needing two lots of antibiotics as my feet took it in turn to go red and painful, I fell back on older resources and bought some ginko biloba tablets.
    My fathers mother's family were midwives and knew their herbs and natural remedies. I read the books my grandmother had from them - some of the things to promote reluctant births would make your hair stand on end.
    Anyway - there seems to be a reduction in the problems with the feet, but I have recently noticed an improvement in my memory - starting with the realisation that things were not what they had been.
    As I am not on any prescribed drugs there was no chance of antagonism, and I am not going to have problems with the increase in circulation which could affect a younger woman - but these things need to be taken into account. Of course men might find better blood flow no problem at all.
    I have got hold of some guitar strings and will see if I have remembered how to play my guitar soon - I can remember playing it, quite clearly now, but I just could not remember how to do it when I picked up the instrument.
     
  10. Annb

    Annb Type 2 · Well-Known Member

    Messages:
    2,458
    Likes Received:
    4,344
    Trophy Points:
    198
    I have been on Metformin for a number of years now (with all the complications you normally hear about until I cut right down on the amount of carbs I was eating). My memory has always been bad, but I do notice that it is getting worse. It could very easily be old age just making a pre-existing weakness, worse, because I am a bit long in the tooth but I panicked a bit yesterday when I had to change my Libre sensor and I couldn't think how to do it. I was staring at the applicator and wondering why there was no needle in it. Eventually realised that I had to put the sensor itself into the applicator and all was well, but how could I have forgotten that?

    I have had a problem with remembering what I was supposed to be doing since I was a child (eg running a mile and a half to the dairy to buy a pint of milk for my mother, paying for it and running all the way home without it; then having to run back again to get it - a 6 mile run for a pint of milk!)

    But, I don't think it's Metformin.
     
  • Meet the Community

    Find support, connect with others, ask questions and share your experiences with people with diabetes, their carers and family.

    Did you know: 7 out of 10 people improve their understanding of diabetes within 6 months of being a Diabetes Forum member. Get the Diabetes Forum App and stay connected on iOS and Android

    Grab the app!
  • Tweet with us

  • Like us on Facebook