Metformin. how soon does it show effect on hba1c?

[kokhongw]

my next hba1c is february. i would really like to do better with the diet to avoid dose increase. any suggestions?

This study may be a little dated...2010 but in general things haven't changed that much. Perhaps the newer SGLT2 performs a little better

RESULTS
A total of 61 trials reporting 103 comparisons met the selection criteria, which included 26,367 study participants, 15,760 randomized to an intervention drug(s), and 10,607 randomized to placebo. Most OAD agents lowered A1C levels by 0.5−1.25%, whereas thiazolidinediones and sulfonylureas lowered A1C levels by ∼1.0–1.25%. By meta-regression, a 1% higher baseline A1C level predicted a 0.5 (95% CI 0.1–0.9) greater reduction in A1C levels after 6 months of OAD agent therapy. No clear effect of diabetes duration on the change in A1C with therapy was noted.

CONCLUSIONS
The benefit of initiating an OAD agent is most apparent within the first 4 to 6 months, with A1C levels unlikely to fall more than 1.5% on average. Pretreated A1C levels have a modest effect on the fall of A1C levels in response to treatment.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909079/

If this chart has been the result of taking a special newly prescription medication, it would have been a billion dollar blockbuster drug...unfortunately it is thru freely available carbs reduction and intermittent fasting. HbA1c reduction of 5.5% within 12 weeks...maintained at < 5.5% for another 56 weeks.