Metformin & Testosterone Levels

[finsit]

I have come across couple of studies which is quite eye-opening. Mind you that there was non-diabetic control group as well where the Free testosterone went low. If you are on Metformin for long, can you relate to this?

Metformin leads to significant reduction in testosterone levels, sex drive and induction of low testosterone-induced erectile dysfunction, whereas; sulfonylurea leads to significant elevation in testosterone levels, sex drive and erectile function.

full text:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5296448/

https://pubmed.ncbi.nlm.nih.gov/11707532/

 

[EllieM]

Interesting studies but really small sample sizes?

 

[searley]

Or maybe it just hypogonadism is another endocrine ailment like diabetes and often go hand in hand

I have to take testosterone and am not on metformin