Im on a low carb diet. I am. losing weight and my sugars are lowering as im testing. im very sensitive to medication and tend too have every side effect going. diabetic nurse is useless and is actually just a normal nurse. my Gp has said I have been calling too much recently and are monitoring how much I call, so im changing Gps. i feel alone and lostIt's unusual to have problems with modified release Metformin but a few people are unable to tolerate it. You may have to stop taking it and talk to the GP. Metformin never helps that much anyway and there are a few other drugs which work in different ways. Diet is always the highest priority with T2. Have you reduced the carbs in your diet?