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New Insulin Delivery System

Takes me back to the 1980's, there was excitement then about a capsule you could swallow that would deliver insulin, again the trials in pigs were successful but it never did go much further than that, still we live in hope...............
 
"Once the capsule has reached its target destination, it dissolves and exposes the drug reservoir that is covered with five-millimeter-long needles. The needles pierce the intestines when the tissue contracts, delivering the drug directly."

Eh! - Not for me thank you very much. I hate to think what it would be like passing these things out the other end - especially if you've been constipated and got about 30 needle covered capsules queuing up to be excreted :***:
 
logindetails said:
"Once the capsule has reached its target destination, it dissolves and exposes the drug reservoir that is covered with five-millimeter-long needles. The needles pierce the intestines when the tissue contracts, delivering the drug directly."

Eh! - Not for me thank you very much. I hate to think what it would be like passing these things out the other end - especially if you've been constipated and got about 30 needle covered capsules queuing up to be excreted :***:
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Ewwwww!
 
logindetails said:
"Once the capsule has reached its target destination, it dissolves and exposes the drug reservoir that is covered with five-millimeter-long needles. The needles pierce the intestines when the tissue contracts, delivering the drug directly."

Eh! - Not for me thank you very much. I hate to think what it would be like passing these things out the other end - especially if you've been constipated and got about 30 needle covered capsules queuing up to be excreted :***:
Click to expand...


No pain, no gain ;)
 
Hihi, I think I prefer my meetings with needles as short as possible... Inject and throw away! But swallow... 0_0
 
paul-1976 said:
Think I'll hang on for inhaleable insulin!
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My wife is a patent attorney and worked on patent applications for the delivery system some ten years ago. It may have come under the "not enough money in it" category, because as a diabetic I was interested but never saw the product come to the marketplace. The technology was fine, I'll have to look at what happened.
 
Notwithstanding the needles, I still can't see how this sort of oral system is going to be as flexible as pumps or MDI. How many different capsules would you need to be able to vary your dose.
Now smart insulin that would be different.
http://jdrf.org/smartinsulin/
 
paul-1976 said:
Sounds painful! :woot::jimlad: Think I'll hang on for inhaleable insulin!

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You'd need a daily dose of chilli to keep the needles passing through.

Now we just need someone clever to come up with a pun on the biblical needles passing through the ar$e of a camel
 
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