I asked that question yesterday on the 2 hours session where we had a doc in the room. He said much the same thing about the alpha cells losing their reactivity after a while as well, so diminished response from the liver to hypos .
Mo, took yesterday evening's basal down to a nominal 5.5, but with a 20% reduction for a night out.
Thinking of taking the morning one down further to 2.5, and evening to 5.5 when not accounting for any other corrections