A Cochrane review in 1997 illustrated that bariatric surgery was an effective intervention for obesity, demonstrating good results in evidence(13). In contrast to the bleak long term results obtained by dietary and pharmacotherapy treatments bariatric surgery has been shown to result in excess weight loss of over 61% in a meta-analysis(14) which was sustainable at 10 – 15 year follow up. The ‘Swedish Obese Subjects’ study compared surgical, pharmacological, and lifestyle alteration therapy, demonstrating a tenfold increase in the success of surgical intervention compared to non surgical after 10 years(15-17).
More importantly this success can be shown in the reduction of obesity related mortality, and morbidity. Sjöström et al(18) demonstrated in 2007 that surgery decreased the overall mortality of obese patients, with a hazard ratio compared to the control group and adjusted for age, sex, and risk factors, of 0.71 (p=0.001). An earlier study by Pories et al(19) in 1995 also demonstrated the impact of bariatric surgery upon type II diabetes stating “No other therapy has produced such durable and complete control of diabetes mellitus.” This study also demonstrated bariatric surgery to correct or alleviated other co-morbidities of obesity, including hypertension, sleep apnoea, cardiopulmonary failure, arthritis, and infertility stating “Gastric bypass is now established as an effective and safe therapy for morbid obesity and its associated morbidities.“
13. Glenny AM, O'Meara S, Melville A, Sheldon TA, Wilson C. The treatment and prevention of obesity: a systematic review of the literature. Int J Obes Relat Metab Disord 1997;21(9):715-37.
14. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA 2004;292(14):1724-37.
15. Torgerson JS, Sjostrom L. The Swedish Obese Subjects (SOS) study--rationale and results. Int J Obes Relat Metab Disord 2001;25 Suppl 1:S2-4.
16. Sjostrom CD, Peltonen M, Wedel H, Sjostrom L. Differentiated long-term effects of intentional weight loss on diabetes and hypertension. Hypertension 2000;36(1):20-5.
17. Silecchia G, Perrotta N, Boru C, Pecchia A, Rizzello M, Greco F, et al. Role of a minimally invasive approach in the management of laparoscopic adjustable gastric banding postoperative complications. Arch Surg 2004;139(11):1225-30.
18. Sjostrom L, Narbro K, Sjostrom CD, Karason K, Larsson B, Wedel H, et al. Effects of bariatric surgery on mortality in Swedish obese subjects. N Engl J Med 2007;357(8):741-52.
19. Pories WJ, Swanson MS, MacDonald KG, Long SB, Morris PG, Brown BM, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus. Ann Surg 1995;222(3):339-50; discussion 350-2.