My doctor has just put me on omeprazole, I take one in the morning and one at tea time and my sugar level has risen through out the night plus during the day. Has anyone else found this? Been in a new job for 6 weeks and struggling to get sugar levels sorted as gone from running around all day to sitting down. Been doing fasting test etc as on a pump. Been putting insulin up and it does not seem to be having any effect what so ever. Any advice gratefully received. Have been diabetic for 30 years times like this does your head in!!!!
Yep been there too! The PPI meds reduce stomach acid so things take longer to digest, including meds, I was switched from standard Metformin to a generic substitute called Sukkarto, and I found that the enteric coating on the new pills was not dissolving. Turns out the manufacturer uses shellac varnish to provide slow release but in my case I had no release at all, so I had to go back to GP to get my proper meds re-installed pdq.
Other things get affected by the Prazoles. Vitamin B absorbtion gets interferred with, and in my case led to iron deficiency anaemia. Iron tabs to overcome anaemia are contraindicated with the PPI meds too so I was adding necessary expense to my prescription simply because of the PPI without benefitting from it. I fought back by moving the PPI and the heart med it was prescribed for to being last thing at night, and so far it is working out, I would suggest that you ask the GP to consider using Lansoprazole instead since it is not so agressive. Omeprazole ist the worst one of the family for interfering with other meds
https://www.fda.gov/Drugs/DrugSafety/ucm245011
https://www.fda.gov/Drugs/DrugSafety/ucm290510.htm?source=govdelivery
Of course here in the UK we don't bother with what the Americans think of how to treat patients, so here in the UK there are no warnings in place and these PPI's are considered to be very safe and very cost effective, according to NICE.
Edit to say that I am a T2D and not an insulin user, so cannot comment on this.