Cautions Paracetamol
alcohol dependence; max. daily infusion dose 3 g in patients with hepatocellular insufficiency, chronic alcoholism, chronic malnutrition, or dehydration; interactions: Appendix 1 ("paracetamol")
Hepatic impairment
dose-related toxicity—avoid large doses; see also Cautions
Renal impairment
increase infusion dose interval to every 6 hours if eGFR less than 30 mL/minute/1.73 m2; note also sodium content of effervescent tablets (see under relevant preparation entry)
Side-effects
side-effects rare, but rashes, blood disorders (including thrombocytopenia, leucopenia, neutropenia) reported; hypotension, flushing, and tachycardia also reported on infusion; important: liver damage (and less
Byetta
Side-effects
gastro-intestinal disturbances including nausea, vomiting, diarrhoea, dyspepsia, abdominal pain and distension, gastro-oesophageal reflux disease, decreased appetite; headache, dizziness, agitation, asthenia; hypoglycaemia; increased sweating, injection-site reactions; antibody formation; less commonly pancreatitis (see Cautions above); very rarely anaphylactic reactions; also reported constipation, flatulence, eructation, dehydration, taste disturbance, renal impairment, drowsiness, rash, pruritus, urticaria, and angioedema
bowell said:Lucky to only have Arthritis Gout TIA with T2...
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