yes - the degludec tresiba vs lantus DEVOTE trial showed same HbA1cs and weights, but significantly fewer hypos on the Lantus. You have a good doctor if he suggests tresiba cos it is significantly more expensive. The tresiba is human insulin with some side chains added to make it last longer, whereas the Lantus is human insulin with some molecules altered to make it less soluble in the subcutaneous tissues - this slight difference might or might not be relevent in the very long run, but only time will tell.