It's not that unusual, I inject at least 120 units of Humulin S and 120 of Insulatard a day. The current thinking is that I am allergic to insulin so my immune system is destroying a large part of that. I am underweight so can't really blame resistance.nmr1991 said:You sure weren't injecting water instead of 110 units of novorapid per day? cos i'd be dead if I injected that and not had a mountain of sugar to eat. Either that or the insulin isn't working for you or you built up some super resistance to it because 110 units is a hell of alot, enough to put you in a diabetic coma 10x over, or maybe a little less.