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Medscape Medical News
Type 1 Diabetes Life Expectancy Still 12 Years Short of Norm
Marcia Frellick
April 07, 2016
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Two large new studies have found that, although there have been life-expectancy gains for people with type 1 diabetes, similar gains have been seen in the general population, thus failing to narrow a gap that stands at nearly 12 years.
Both studies were published online in
Diabetologia, one detailing findings from Australia and the other from Sweden over the past 2 decades.
The two sets of authors both conclude that a multipronged approach is required to improve life expectancy for those with type 1 diabetes, including better glycemic control, as well as more focus on preventing chronic cardiovascular disease in these patients, who are at high risk of the latter. This should include more concentration on smoking cessation and better lipid management.
Penning
a commentary that discusses both studies, Lars Stene, PhD, of the Norwegian Institute of Public Health, Oslo, says these two "impressively large population-based registries" have "documented a [life-expectancy] gap [in type 1 diabetes] compared with the general population that has…remained largely unchanged since the turn of the millennium."
The two papers fill "some knowledge gaps," he notes, "but others remain."
Australian Findings Broadly Generalizable, Similar to Swedish Ones
In the
first study, Lili Huo of the Baker IDI Heart and Diabetes Institute, in Melbourne, Australia, and colleagues derived mortality rates of Australians with type 1 diabetes listed on the National Diabetes Services Scheme (NDSS) between 1997 and 2010 (n = 85,547) by linking them to the National Death Index.
Because the contemporary study was nationwide, authors said the results likely would translate to similar Western countries.
A total of 5981 deaths were found among the type 1 diabetes patients during the 902,136 person-years of follow-up.
While life expectancy in 2004–2010 improved for those with type 1 diabetes compared with 1997–2003, it also increased in the general population, and therefore the gap didn't close.
They found that Australian type 1 diabetic patients had an estimated loss in life expectancy at birth of 12.2 years compared with the general population (11.6 years less for men and 12.5 years less for women.)
For type 1 patients, estimated life expectancy at birth was 66.7 (men) and 70.9 years for women.
"We observed marked reductions in life expectancy across all age intervals, even in the very old, as compared with the general population," the authors write.
Death from endocrine and metabolic disease was the major factor in lost years between the ages of 10 and 39 years — this reduced with advancing age, while the contribution of deaths from circulatory disease increased as people got older. Continue Reading
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