• Guest - w'd love to know what you think about the forum! Take the 2025 Survey »

Has anyone ever had a fasting insulin test on the NHS?

Exactly how much blood is needed? It does seem to be a lot. Can the blood containers be taken to a surgery for a venous sample, or does it have to be one of their special centres?
You can get the blood drawn at one of their centres for I think £25 there's one not too far away from me..but I'll try the finger prick and see how it goes on Monday morning. Its a fairly big container but smaller than the usual blood test ones so hopefully a few fingers pricks and squeezes will be ok. The 4 lancets look a bit daunting though...
 
Last edited:
One of the current theories is that the beta cells die slowly once they have so much fat in them that they can't work.
Is that all beta cells or just the pancreas ones, I wonder?
Because if all then liver, kidneys and heart could be vunerable too. Some of the systems rely on beta cells too, I believe. Not sure about circulatory system other than heart. Endocrine system definitely, as all type1s know that beta cell death is type1 cause.
 
I don't know about fat build up in the kidneys and heart, but I expect cell death in the liver. However, the liver can regrow its cells at a fast rate.
 
Insulin resistance is measured by comparing fasting insulin to fasting glucose. A complex set of equations is solved to find the "Insulin Resistance" that is consistent with the two numbers. The result has been shown to give the same answer as an insulin clamp test.

To do an "insulin clamp test" you pump glucose into one of the "victims" arms, and insulin into the other arm, you then increase the both so as to keep BG at a set number with the insulin being at least 10 (if not 100) times more than any one's body can produce. You then look at the amount of the insulin compared to the glucose. Every time the test is done, someone's insulin resistance increases, as high insulin + high glucose leads to insulin resistance.
A sliding scale in labour (twice) and whilst having an op (sterilised; maybe) is very similiar to which you describe. Does those increase my IR too?
 
A sliding scale in labour (twice) and whilst having an op (sterilised; maybe) is very similiar to which you describe. Does those increase my IR too?

Maybe, but it will not be much of an increase in IR as they keep the levels as low as they can, unlike an "insulin clump" where they put the levels as high as they can. (There is a reason why a lot of medical research is done in a room next to an intensive care unit with an empty bed....)
 
I don't know about fat build up in the kidneys and heart, but I expect cell death in the liver. However, the liver can regrow its cells at a fast rate.
I have most of my atherosclerosis in LAD and now wondering if beta cell death have contributed to it's attraction. Very common cause of heart attack death in obese patients.
I will investigate further. I am now vunerable to instant death due to its collection but if due to beta cell death many can be saved maybe in the future. Let's see.
All worth investigating, in my book. Regenerating cells is the medicine of the future, it seems.
 
The problem I have - is I had a quick look around the site and before I knew it had a shopping basket in large four figures.... :)
They are all so tempting.... and how often will I have to re-test... might need to get another job...

Fleegle - There are lots of these online blood test sites.

I haven't tried any of the sites personally, as my GP is usually pretty accommodating, if I can build a credible case for something. I haven't asked for a fasting insulin test, and to be honest, I doubt I could, hand on heart, find it in me to even try to build a case for it, for myself.

However, ignoring the preceding paragraph of waffle, if you have a look at some of the other site, including Blue Horizon, who get pretty decent press on the thyroid fora, they often do offers, or package up, and discount associated tests, or even sometimes do a "buy x number and get £Y off at the checkout", but those offers seem to change around.

Enjoy!
 
Fleegle - There are lots of these online blood test sites.

I haven't tried any of the sites personally, as my GP is usually pretty accommodating, if I can build a credible case for something. I haven't asked for a fasting insulin test, and to be honest, I doubt I could, hand on heart, find it in me to even try to build a case for it, for myself.

However, ignoring the preceding paragraph of waffle, if you have a look at some of the other site, including Blue Horizon, who get pretty decent press on the thyroid fora, they often do offers, or package up, and discount associated tests, or even sometimes do a "buy x number and get £Y off at the checkout", but those offers seem to change around.

Enjoy!
Thank you - I am going to have a good look.
 
The more I read on this thread the more I'd love my insulin resistance quantified.
I'd be willing to be put forward for more research or have my bloods collected before bariatric surgery to see how much difference it will make to improving IR.
I could ask bariatric specialist when I meet him face to face. Only seeing dn for next 6mths now. Endocrologist hasnt the funding for taking IR further in Sunderland where the first bariatric surgery unit was born.
Funding would have to come from bariatric unit money, I guess but I believe nhs unit not private. If Sunderland bariatric unit did private bariatric ops too then money could be used to fund more research, maybe?
 
Given how close Sunderland is to Newcastle I think you can work out who you should email.......
 
Ok so latest update.. no way could I fill the tube from a finger prick so have booked in for a venous sample to be taken. Very helpful guy on the phone just had to pay an extra £25 for the phlebotomist and the hospital is pretty local to us as well. Have to wait for a new kit and make appointment. Will update when I hear something.
 
Ok so latest update.. no way could I fill the tube from a finger prick so have booked in for a venous sample to be taken. Very helpful guy on the phone just had to pay an extra £25 for the phlebotomist and the hospital is pretty local to us as well. Have to wait for a new kit and make appointment. Will update when I hear something.

I have this mental picture of you with plasters and bruises on every finger.

Blue Horizon also seem to be pretty "generous" in the approach to failed collections. I know from observation that those not used to pricking their fingers can recount some quite dramatic experiences.
 
Looking at the volume they're expecting from you I had begun to worry that you might've had to send them a whole finger for them to squeeze themselves......
:nailbiting:

I thought the same when I looked at the instructions on their website. It must be pretty much impossible. No wonder they supply plasters with the kit!
 
Just wondering if anyone has ever managed to get one of these. I'm interested to see what my fasting insulin level is but have just been informed by my surgery that this test os not available on the NHS and ... wait for it.. the Diabetes Nurse couldn't see that it would be any use to my condition. So either she is covering her ignorance, genuinely thinks that it won't be useful or doesn't want to let me have it. Hence my question.
No-one that I have spoken to so far in the HCP realm seems to have ever heard of it although I do believe that it is fairly common in the US.
Looks like more private medicine for me if I want one.

I have never had this done on the NHS. I did organise it privately. It was one of the figures that the Prof Tim Noakes asked me to get as part of the study I took part in.

the test came back at 20 - which my doctor said was within "normal" range at the time - that being upto 25.
As I understand it the correct ideal range is something like 3-6 and thus my 20 indicates significant insulin resistance.
Summary of that study
29 patients on LCHF composition average 68% fat, 12% carbs,20% protein
all participants had lost weights average 21kg
18 participants had hab1C under 42m only 4 above 48 ( 1 still 70 and 1 at 90)
15 participants had fasting glucose levels that day of 6 or under , 2 above 8 ( 1 at 13.5 and the other at 16)

Fasting Insulin was particularly interesting
Only 4 participants had a fasting insulin level under 6 ,
5 had fasting insulin over 15 - including me - one had fasting insulin of about 28 .

Thus despite normal glucose levels and near normal Hba1c' the cohort still have relatively high fasting insulin compared to normal.
I am assuming that my own high numbers are a function of relative time on the diet and as such should come down over time ( I was the shortest duration participant i.e. 6 months since diagnosis and 6 months on LCHF.

The study itself considered that 8 individuals could effectively be in " remission" i.e. no actual signs of diabetes and none of fasting insulin, hba1C or fasting glucose tests outside the normal ranges .

Of the 11 participants who were taking insulin prior to LCHF 8 of them have come off it entirely, 2 reduced their dosage and 1 had not changed it at all.

One area that now interests me a great deal is the two participants on the LCHF diet but still with very high Hba1C and fasting glucose numbers. There figures seem rather similar to my friend who I have written about on another thread.

These appear to be individuals who do not respond to LCHF , however looking at the interim data they do not appear to have responded to insulin either .

This makes me wonder if in fact the issue is that it is not that there are individuals with T2 diabetes do not respond to an LCHF diet, it is instead that these individuals may not in fact have T2 diabetes. instead they have type B insulin receptor antibodies - an auto-immune disorder with an entirely different treatment protocol. Maybe this is not quite as uncommon as suggested . Given the standard way that anyone presenting with high blood sugars is treated - it would seem entirely possible for this to be the case. I have sent the details to the Tim Noakes study for investigation.
 
[QUOTE="DCUKMod, post: 1532582, member: 345386
Blue Horizon also seem to be pretty "generous" in the approach to failed collections. I know from observation that those not used to pricking their fingers can recount some quite dramatic experiences.[/QUOTE]

Same with Medi checks they have put the venous testing kit in the post and asked me to call the hospital and make an appointment when it arrives. They did ask that I sent the unused kit back which I will do. But have only been charged extra for the blood letting and not for the test itself.
 
I have never had this done on the NHS. I did organise it privately. It was one of the figures that the Prof Tim Noakes asked me to get as part of the study I took part in.

the test came back at 20 - which my doctor said was within "normal" range at the time - that being upto 25.
As I understand it the correct ideal range is something like 3-6 and thus my 20 indicates significant insulin resistance.
Summary of that study
29 patients on LCHF composition average 68% fat, 12% carbs,20% protein
all participants had lost weights average 21kg
18 participants had hab1C under 42m only 4 above 48 ( 1 still 70 and 1 at 90)
15 participants had fasting glucose levels that day of 6 or under , 2 above 8 ( 1 at 13.5 and the other at 16)

Fasting Insulin was particularly interesting
Only 4 participants had a fasting insulin level under 6 ,
5 had fasting insulin over 15 - including me - one had fasting insulin of about 28 .

Thus despite normal glucose levels and near normal Hba1c' the cohort still have relatively high fasting insulin compared to normal.
I am assuming that my own high numbers are a function of relative time on the diet and as such should come down over time ( I was the shortest duration participant i.e. 6 months since diagnosis and 6 months on LCHF.

The study itself considered that 8 individuals could effectively be in " remission" i.e. no actual signs of diabetes and none of fasting insulin, hba1C or fasting glucose tests outside the normal ranges .

Of the 11 participants who were taking insulin prior to LCHF 8 of them have come off it entirely, 2 reduced their dosage and 1 had not changed it at all.

One area that now interests me a great deal is the two participants on the LCHF diet but still with very high Hba1C and fasting glucose numbers. There figures seem rather similar to my friend who I have written about on another thread.

These appear to be individuals who do not respond to LCHF , however looking at the interim data they do not appear to have responded to insulin either .

This makes me wonder if in fact the issue is that it is not that there are individuals with T2 diabetes do not respond to an LCHF diet, it is instead that these individuals may not in fact have T2 diabetes. instead they have type B insulin receptor antibodies - an auto-immune disorder with an entirely different treatment protocol. Maybe this is not quite as uncommon as suggested . Given the standard way that anyone presenting with high blood sugars is treated - it would seem entirely possible for this to be the case. I have sent the details to the Tim Noakes study for investigation.

That's some really interesting information and observations you have given us there Cherry, many thanks. I hope you'll update us about it if you ever hear anything back from the Tim Noakes study.

I'll leave it there coz I don't want to derail BB's thread, which I'm following with great interest. (to see if it might be worth me getting it done) :)
 
That's some really interesting information and observations you have given us there Cherry, many thanks. I hope you'll update us about it if you ever hear anything back from the Tim Noakes study.

I'll leave it there coz I don't want to derail BB's thread, which I'm following with great interest. (to see if it might be worth me getting it done) :)

Thank's I was going to do it as a separate thread, but so much of the info is intermingled with the fasting insulin test it seemed more sensible to leave it in the one place as I probably have more data on the outcome of fasting insulin in T2 diabetics than most others, since being able to get the thing actually tested seems to be rare as hen's teeth . I will post any other observations in separate thread if they come up. I have also separately asked some questions regarding poor responses to the LCHF diet resulting in high figures including fasting insulin on the thread Type B insulin resistance.

I personally will be astonished if @bulkbiker has anything other than exemplary fasting insulin figures given everything else .... oh to be @bulkbiker LOL
 
Thanks again; I think you're right that your info links in with what @bulkbiker's looking for, I just didn't want anything that I might say to throw a wobly into the mix. I'll take a look at that other thread shortly (just off for my walk).

I personally will be astonished if @bulkbiker has anything other than exemplary fasting insulin figures given everything else .... oh to be @bulkbiker LOL

Couldn't agree more; BB - how I wish I had half your determination, and stamina :)
 
the test came back at 20 - which my doctor said was within "normal" range at the time - that being upto 25.
As I understand it the correct ideal range is something like 3-6 and thus my 20 indicates significant insulin resistance.

Can you tell me where the ideal normal ranges can be found? There seems to be some confusion, and there are different measurement units knocking about when you search for answers. The majority of the sites I've looked at say under 25mIU/L or under 174 pmol/L. Who says it should be under 6?
 
Back
Top