• Guest - w'd love to know what you think about the forum! Take the 2025 Survey »

Type 2 Glicklazide

C

Chris181

Member
Messages
20
Type of diabetes
Type 2
Treatment type
Tablets (oral)
Glicklazide seems to work well for me but my doc says it will burn out my beta cells, leading to low insulin. I have not been able to find any information on this, but I did read that we loose our betas, with or without Glicklazide. I also foun studies that say that it is an anti oxide and prolongs the life of beta cells. What to believe? I would like to hear from members who have been on Glicklazide for a few years, and what has the effect on hba1c, and any other information of importance. Thanks
 
I was put on glicazide, only a few days ago. My DN increased the dose to 80mg and told me that they don't like to give a higher dose because it is so hard on the pancreas.

I was put on glic because I need steroids. However, I have been peaking at over 18 and elevated readings last around 8 hours. I took my last glic today and will start insulin tomorrow.

Sorry, it doesn't really answer your question.
 
xfieldok said:
I was put on glicazide, only a few days ago. My DN increased the dose to 80mg and told me that they don't like to give a higher dose because it is so hard on the pancreas.

I was put on glic because I need steroids. However, I have been peaking at over 18 and elevated readings last around 8 hours. I took my last glic today and will start insulin tomorrow.

Sorry, it doesn't really answer your question.
Click to expand...

Thank you. How long were you on Glicklazide?
 
Gliclazide works by forcing the pancreas to produce extra insulin. It therefore puts a lot of strain on the pancreas.

If someone already has their own insulin in quantity, there seems little point in forcing the pancreas to produce even more.
 
Who knows? I was on 320mg Gliclazide (yes, max dose) for several years and in the last year of it I was refused insulin; thank you GP. I'll never know whether my beta cells death was aided by that amount of Glic but my insulin production is now quite low. In retrospect I was a LADA and should have had insulin earlier. My advice to anyone would be to play it safe and don't go beyond 80mg without discussing insulin and insisting on it if LADA is suspected. Any T2 who has excess weight probably shouldn't have either Glic or insulin as the problem is probably insulin resistance with lots of insulin in the body. A slim T2 should ask for the tests for T1.
 
I'm not saying there is a definate realtionship but I was on Glic for three and a half years, latterly taking 80mg twice daily. Ended up with chronic pancreatits. Now on insulin.
My own, non medical guess is that the Glic knocked the stuffing out of my pancreas.
 
I was on gliclizide for 10 years - started off on maximum and slowly dropped dose over the years as I lost weight. Dropped it totally in January and went keto (less than 20g carb a day) last Hba1c was 46 a few weeks ago - no longer on gliclizide and getting along fine on keto
 
Chris181 said:
Glicklazide seems to work well for me but my doc says it will burn out my beta cells, leading to low insulin. I have not been able to find any information on this, but I did read that we loose our betas, with or without Glicklazide. I also foun studies that say that it is an anti oxide and prolongs the life of beta cells. What to believe? I would like to hear from members who have been on Glicklazide for a few years, and what has the effect on hba1c, and any other information of importance. Thanks
Click to expand...
I am and have been a user for over 4 years, but I cannot comment on medical matters.
 
Daibell said:
Who knows? I was on 320mg Gliclazide (yes, max dose) for several years and in the last year of it I was refused insulin; thank you GP. I'll never know whether my beta cells death was aided by that amount of Glic but my insulin production is now quite low. In retrospect I was a LADA and should have had insulin earlier. My advice to anyone would be to play it safe and don't go beyond 80mg without discussing insulin and insisting on it if LADA is suspected. Any T2 who has excess weight probably shouldn't have either Glic or insulin as the problem is probably insulin resistance with lots of insulin in the body. A slim T2 should ask for the tests for T1.
Click to expand...

LADA?
Thanks
 
Bluetit1802 said:
Gliclazide works by forcing the pancreas to produce extra insulin. It therefore puts a lot of strain on the pancreas.

If someone already has their own insulin in quantity, there seems little point in forcing the pancreas to produce even more.
Click to expand...

Any idea where the study was done, or any links? Chris181
 
miahara said:
I'm not saying there is a definate realtionship but I was on Glic for three and a half years, latterly taking 80mg twice daily. Ended up with chronic pancreatits. Now on insulin.
My own, non medical guess is that the Glic knocked the stuffing out of my pancreas.
Click to expand...

Thanks for the info Miahara... Chris181
 
I disagree with some of the comments in this thread, but Forum rules prevent me from responding
 
Back
Top