Wow that’s interesting. I’m newly diagnosed so my medical team are a bit nervous to change anything yet but I will have to do my research as it may be something I can benefit from.
If my basal needs are reduced then the risk of hypoglycaemia would reduce as you would have less background insulin in your body so anything like exercise would be less likely to cause hypoglycaemia
Hi TZ.
OK? Your in a situation newly diagnosed, & in the "honeymoon" with a semi active pancreas doing the "dying swan."
With exogenous insulin on board picking up the slack. (Let's put bolus aside for a moment.)
You're contemplating adding a drug which potentially increases insulin sensitivity & retards liver dump.
Lantus can be pretty unstable at the best of times in my experience...
Yes, I am interested in T1 experience with metformin because it seems like a no-brainer for T1s to me. T1s make too much glucagon because insulin is injected under the skin and doesn't come from the pancreas. In non-diabetics, the liver stops supplying glucose when it sees insulin, which comes through the portal vein from the pancreas next to it. T1 livers never get that message. So something that inhibits liver glucose would seem to make sense. But Metformin is not considered as T1 treatment for some reason. I tried it a while back and it seemed to reduce blood glucose. But the effect also seemed to be inconsistent, so I stopped it. I was eating high-carb back then. I want to try it again now that my control is much better.
Mark, a revised insulin delivery system putting it right into that upper intestine location area where the pancreas sits, could be a more viable option? (In therory.) How.? I'm stumped.
The OP is looking for T1s experience of the drug "Pramlintide."
Can we please keep the subject matter within the confines of those with this personal experience. Or pointing in the specific direction of..
Thanx..