Could rinse aid residue be harmful and part of the cause of mellitus?

[Lamont D]

Food doesn't make healthy people diabetic.
A normal working gut and metabolic tem is perfectly able to cope with all sorts of food.

Have you not heard of intolerance or allergies?
I have had lactose (dairy) intolerance since I was born!
Allergies from food can be from birth!
The gut biome is so huge and everyone is so different in its entirety. Bacteria good and bad in the billions!
So which one is considered normal?

Food has a huge impact on your health, and the causes of endocrine conditions such as T2 are diverse and in some cases unknown.

Have you not heard that arsenic is fine in very, very, very small doses?
But so is water!
Everything in moderation!

 

[Oldvatr]

Have you not heard of intolerance or allergies?
I have had lactose (dairy) intolerance since I was born!
Allergies from food can be from birth!
The gut biome is so huge and everyone is so different in its entirety. Bacteria good and bad in the billions!
So which one is considered normal?

Food has a huge impact on your health, and the causes of endocrine conditions such as T2 are diverse and in some cases unknown.

Have you not heard that arsenic is fine in very, very, very small doses?
But so is water!
Everything in moderation!

I maintain that the grade of fuel going into the craburettor is more important on influencing performance than the sump oil. But both are necessary.

 

[ON A MISSION 4 REMISSION]

experiments with faecal transplants in vitro have not managed to either cure or trigger T2D as a result of the transfer.

In vivo experiments with autologous FMT however are promising and ongoing, at least in type 1's.

 

[Oldvatr]

In vivo experiments with autologous FMT however are promising and ongoing, at least in type 1's.

Here is a study for T2D. It is a mouse study, and the way they induce metabolic dysfunction in mice is to overfeed them with a high fat diet and kill off their beta cells with a powerful chemotherapy drug normally used to kill off cancer tumours. It does produce an effect similar to diabetes, but is not diabetes so may be a weakness in the study.

Promising Treatment for Type 2 Diabetes: Fecal Microbiota Transplantation Reverses Insulin Resistance and Impaired Islets

Type 2 diabetes is a common metabolic disorder related to insulin resistance, or deficiency of insulin secretion, caused by decreased insulin sensitivity and destruction of islet structure and function. As the second human genome, the microbiota has been observed to have a growing relationship...

www.frontiersin.org

Be aware that mice have two sources of insulin producing tissue and do not have a single pancreas like humans. If they clobber one source with directed injection, then the other source may well take over and compensate.

 

[KennyA]

Food doesn't make healthy people diabetic.
A normal working gut and metabolic system is perfectly able to cope with all sorts of food.
Except arsenic and other toxic fodder.

D2 is the body's regulator (carb.urettor) gone awry.

Most of the recent studies do show that you can tell a diabetic person from their gut flora.

If you stop the LC diet do you think you will stay DX?
Maybe you are just in D2 relapse as long as you don't eat carbs.
To change your
One of the most recent Dec 2022 research studies, shows that diabetic people actually have an abundance of a butyrate producing bacteria.
Which should help protect the gut?
Alas its a species that doesn't use fiber but eats vitamins especially B and D to produce the butyrate.

So the artificial adding of vitamins to white bread, cereals and a lot of foods may turn out to be a long lasting detrimental effect on the western diet's gut biome.

I don't think western food producers help.

Another daft thing they have done is to replace normal sugar in everything with High Fructose Corn Syrup just to make more money.
HFCS should really be banned or taxed so much old fashioned normal sugar is cheaper and used again.

Carbs don't create D2, people's gut biome does.
By creating internal inflammation, and allowing LPS and bacteria to run amok.
You are what your intestinal bacteria eat ...
... and expel.

As requested before, do you have any links to the actual studies you mention?

 

[Angela64]

Well, I had no symptoms what so ever till I went ‘vacant’ HBa1C was 134, husband thought I’d had a stroke or TIA. It seems that I have Haemochromatosis in my family, sister and brother carriers. I’ve been nagging GP for months for a test, iron level at one point was well over 900‍ Finally, got a test recently and waiting to see results. I have SVT, PAF as well as the T2 now. Seems Diabetes and PAF/ AF may be implicated.

 

[Lupf]

According to a study published in the Journal of Allergy and Clinical Immunology, professional dishwashers that use rinse aids could potentially harm the protective layer of the gut. The study employed in vitro methodologies and studied the effects of the dishwashing components, including rinse aids, on cultured cells, organoids, and a gut-on-a-chip model. Results showed that professional rinse aid, at a dilution of 1:20000, was found to be cytotoxic and responsible for compromising the epithelial barrier integrity through disruption of cellular tight junctions. This could lead to increased cytotoxicity of human intestinal epithelial cells, as supported by the data from the study.

Alcohol ethoxylate is a "non ionic surfactant" which is the main ingredient in rinse aid. It helps water slide off the dishes, glasses etc.
So imagine what it does to the intestinal muscosa layer?

Perhaps it isn't so much the western diet causing mellitus, but the chemicals in our life?

??
Do you have a dish washer?
Do you use rinse aid?
Have you had a dish washer before or after being diagnosed with melittus?

Do you have a link to this study?

If washing dishes were a significant effect in causing diabetes then there would be a much larger occurrence of diabetes in women than in men.
Whereas the first link on a google finds; 'Men aged 35-54 are almost twice as likely to have diabetes compared to their female counterparts, reveals our new report 'Diabetes in the UK 2009'

 

[LokiTheFiddler]

Do you have a link to the actual study, please?

Here's one to a site quoting it.
Medical abstracts are often behind firewalls and only the abstracts are available.

Gut epithelial barrier damage caused by dishwasher detergents and rinse aids - PubMed

The expression of genes involved in cell survival, epithelial barrier, cytokine signaling, and metabolism was altered by rinse aid in concentrations used in professional dishwashers. The alcohol ethoxylates present in the rinse aid were identified as the culprit component causing the epithelial...

pubmed.ncbi.nlm.nih.gov

 

[KennyA]

Here's one to a site quoting it.
Medical abstracts are often behind firewalls and only the abstracts are available.

Gut epithelial barrier damage caused by dishwasher detergents and rinse aids - PubMed

The expression of genes involved in cell survival, epithelial barrier, cytokine signaling, and metabolism was altered by rinse aid in concentrations used in professional dishwashers. The alcohol ethoxylates present in the rinse aid were identified as the culprit component causing the epithelial...

pubmed.ncbi.nlm.nih.gov

Thank you. It's always a good idea to provide links as making generalised statements like "studies show xyz" is not very helpful. You'll get away with it in the media but not here, where a lot of people are pretty familiar with research.

That link does demonstrate that what they appear to have been doing is establishing that rinse aid is not really good for cells in vitro. I would struggle to apply their stated conclusions to diabetes.

 

[Oldvatr]

Thank you. It's always a good idea to provide links as making generalised statements like "studies show xyz" is not very helpful. You'll get away with it in the media but not here, where a lot of people are pretty familiar with research.

That link does demonstrate that what they appear to have been doing is establishing that rinse aid is not really good for cells in vitro. I would struggle to apply their stated conclusions to diabetes.

Indeed, it is an in vitro study using a microchip to emulate the gut. Not sure how close this is to in vivo, where the cells are alive and working rather than being spread like jam onto a silicon sandwich. With a dilution rate of 20,000 being found to be toxic, this seems to be oversensitive and possibly obsesssive. That dilution is even worse than homeopathic levels. I see that laundry detergents are also as toxic according to the other study they did. Yes, chemicals will have some effect, but they are Generally Considered Safe when used as directed.

I too find no direct link to Diabetes from these studies.

 

[Lupf]

Here's one to a site quoting it.
Medical abstracts are often behind firewalls and only the abstracts are available.

Gut epithelial barrier damage caused by dishwasher detergents and rinse aids - PubMed

The expression of genes involved in cell survival, epithelial barrier, cytokine signaling, and metabolism was altered by rinse aid in concentrations used in professional dishwashers. The alcohol ethoxylates present in the rinse aid were identified as the culprit component causing the epithelial...

pubmed.ncbi.nlm.nih.gov

Thanks for the link.
I agree with @Oldvatr that there is no direct link to diabetes in this study.

The study discusses if there is a link between the use of dishwasher detergents and the increased prevalence of many chronic inflammatory diseases, so nothing related to diabetes.