Ah Jack. Yes it does look that way, but - prepare for the STORM that will come your way for daring to say so. You bored?
You could have a look at what Tim200os said on
here.
That article dates from 1980. Anything a bit recent? Hey ho, what fun it is to pass one's days on the diabetes forum ...
Lucy
I came across the video and remember it being talked about, so I thought it's own thread might be worthwhile, it's nice to have what people know happen shown on a graph
http://www.ncbi.nlm.nih.gov/pubmed/15975714
Ketogenic diet reduces hypoglycemia-induced neuronal death in young rats.
Hypoglycemia is an important complication of insulin treatment in diabetic children and may contribute to lasting cognitive impairment. Previous studies demonstrated that 21-day-old rats (P21) subjected to brief, repetitive episodes of hypoglycemia sustain cortical neuronal death.
The developing brain is capable of utilizing alternative energy substrates acetoacetate and beta-hydroxybutyrate.
In these studies we tested the hypothesis that the developing brain adapted to ketone utilization and provided with ketones during hypoglycemia by eating a ketogenic diet would sustain less brain injury compared to littermates fed a standard diet. Supporting this hypothesis, P21 rats weaned to a ketogenic diet and subjected to insulin-induced hypoglycemia at P25 had significantly less neuronal death than rats on a standard diet. This animal model may provide insight into
http://www.ncbi.nlm.nih.gov/pubmed/14604265
Ketones: metabolism's ugly duckling.
Ketones were first discovered in the urine of diabetic patients in the mid-19th century; for almost 50 years thereafter, they were thought to be abnormal and undesirable by-products of incomplete fat oxidation. In the early 20th century, however, they were recognized as normal circulating metabolites produced by liver and readily utilized by extrahepatic tissues. In the 1920s, a drastic "hyperketogenic" diet was found remarkably effective for treatment of drug-resistant epilepsy in children.
In 1967, circulating ketones were discovered to replace glucose as the brain's major fuel during the marked hyperketonemia of prolonged fasting. Until then, the adult human brain was thought to be entirely dependent upon glucose. During the 1990s, diet-induced hyperketonemia was found therapeutically effective for treatment of several rare genetic disorders involving impaired neuronal utilization of glucose or its metabolic products. Finally, growing evidence suggests that mitochondrial dysfunction and reduced bioenergetic efficiency occur in brains of patients with Parkinson's disease (PD) and Alzheimer's disease (AD). Because ketones are efficiently used by mitochondria for ATP generation and may also help protect vulnerable neurons from free radical damage, hyperketogenic diets should be evaluated for ability to benefit patients with PD, AD, and certain other neurodegenerative disorders.