Hi all! I have indeed being using DuoDerm for the last three sensors. They have not stopped the reaction completely, but have reduced it significantly. I also put another barrier method (Cavillon wipes or lotion - not cream or the plaster won't stick!) on before applying the duoderm.
The main benefit of the duoderm instead of the Compeed for me is that they can be cut. The Compeeds say not to cut them, but the duoderm doesn't leak the hydrocolloid gel when cut, so it can a) be cut into a circle slightly bigger than the sensor, thereby avoiding square edges which lift up and b) have a small hole cut in the centre for the probe to go through without getting all messed up. The duoderms are flexible and stretchy which makes them really comfortable, but might make firing a sensor through them quite hit & miss. I don't get a reaction on the bit where the probe goes, so cutting the hole works for me. Also, being cuttable means that I can buy the bigger sizes (10cm by 10cm) and cut them to the correct size which means I get two sensor barriers out of each plaster reducing the cost!
I find that they stay in place better with a circle of OpSite covering them - I don't think they are designed to last 14 days, but seem to stick better if they don't get wet, so OpSite covering the sensor and duoderm as soon as it has been applied seems to work best - although not exactly aesthetically pleasing!
As a slight aside, I have noticed that the tell-tale red circle of the skin reaction is far less visible when using the Cavillon/duoderm combination and certainly clears up within a few days of removing the sensor, but my skin still has a tendency to break down and removing the sensor/duoderm can cause layers of skin to pull away. To avoid that, I use Zoff alcohol-free adhesive remover wipes which sort of melt the adhesive away so I don't pull at the fragile skin.
It's all a bit of a faff really, but I still think it's worth it to continue using the system.
Smidge