For what it;'s worth, this is a pretty good meta-analysis quantifying the effects of metformin:
https://care.diabetesjournals.org/content/diacare/35/2/446.full.pdf
Short story: Metformin as a monotherapy lowers HBA1c by about 1.12%. This does NOT mean dropping the HBA1c by 1.12% of what it was prior. HBA1c is already measured as a percent (in many places..there are other measures), so this is like going from 8.12% to 7.0%. Metformin combined with other treatments had less effect. I would call 1.12% pretty modest given that my A1C has been as high as 10% before. It's enough to treat borderline diabetics or pre-diabetics into normal readings but wont be enough alone for even intermediate cases.
1.12% A1c is about equivalent to a drop in average glucose levels of about 1.7mmol/l or in the neighbourhood of 35mg/dl.
Hope this helps.
https://care.diabetesjournals.org/content/diacare/35/2/446.full.pdf
Short story: Metformin as a monotherapy lowers HBA1c by about 1.12%. This does NOT mean dropping the HBA1c by 1.12% of what it was prior. HBA1c is already measured as a percent (in many places..there are other measures), so this is like going from 8.12% to 7.0%. Metformin combined with other treatments had less effect. I would call 1.12% pretty modest given that my A1C has been as high as 10% before. It's enough to treat borderline diabetics or pre-diabetics into normal readings but wont be enough alone for even intermediate cases.
1.12% A1c is about equivalent to a drop in average glucose levels of about 1.7mmol/l or in the neighbourhood of 35mg/dl.
Hope this helps.