I've been largely successful in normalizing my BG through diet, exercise, and Metformin. Since 6/2009, when I was diagnosed with T2 diabetes, I started taking 1,000mg of Metfrmin under the care of a general practioner. Since November, I started seeing an endocrinologist and we increased the dose to 1,500mg.
Meantime, I seem to have largely stabilized my BG: my HbA1c fell from 8.4% to 6.4% (no result yet from my test a few days ago but I know it will be in the low 5s). My premeal BG is around 5.3-5.6 and my postprandials are 6.1-6.7. I would like to lower these numbers (especially the premeal) to the extent possible, but I think I've largely "normalized" my BG. My fasting BG is around 4.8.
I eat low carb (about 60g net carbs) and exercise 2-3x a week (burn 750 calories each time), and am moderately active. I've lost about 35 pounds in 2 months and am now within the normal biomass index range. All of my metabolic and lipid panels show normal levels.
Having achieved all this, shouldn't my Merformin dosage go down? I must have been insulin-resistant prior to my diagnosis (fasting BG of 11.7 and frequent breaches of 14). It seems I am reasonably insulin-sensitive as long as I diet. In 11/2009, my endo asked me to increase my dose to 2,000mg. I tried but couldn't because of gastric distress. We compromised at 1,500mg but I'm not sure if this reflects my new conditions.
Now, one curveball with my T2 diabetes is that my C-Peptide is low-normal. It's not out of the normal range but is pretty close to the lower-bound number. In fact, this seems to raise some questions about my T2 status, since most T2s produce high insulin. But what does this indicate regarding Metformin? It seems, then, that trying to increase insulin-sensitivity may be a viable treatment option since I produce little insulin. I'm trying to make sense out of what my endo is telling me to do here.
Meantime, I seem to have largely stabilized my BG: my HbA1c fell from 8.4% to 6.4% (no result yet from my test a few days ago but I know it will be in the low 5s). My premeal BG is around 5.3-5.6 and my postprandials are 6.1-6.7. I would like to lower these numbers (especially the premeal) to the extent possible, but I think I've largely "normalized" my BG. My fasting BG is around 4.8.
I eat low carb (about 60g net carbs) and exercise 2-3x a week (burn 750 calories each time), and am moderately active. I've lost about 35 pounds in 2 months and am now within the normal biomass index range. All of my metabolic and lipid panels show normal levels.
Having achieved all this, shouldn't my Merformin dosage go down? I must have been insulin-resistant prior to my diagnosis (fasting BG of 11.7 and frequent breaches of 14). It seems I am reasonably insulin-sensitive as long as I diet. In 11/2009, my endo asked me to increase my dose to 2,000mg. I tried but couldn't because of gastric distress. We compromised at 1,500mg but I'm not sure if this reflects my new conditions.
Now, one curveball with my T2 diabetes is that my C-Peptide is low-normal. It's not out of the normal range but is pretty close to the lower-bound number. In fact, this seems to raise some questions about my T2 status, since most T2s produce high insulin. But what does this indicate regarding Metformin? It seems, then, that trying to increase insulin-sensitivity may be a viable treatment option since I produce little insulin. I'm trying to make sense out of what my endo is telling me to do here.
), and I do think it helps me restrain my appetite. 
