Another nail in the carb coffin

[Oldvatr]

"
Gene therapy treatment for diabetes often focuses on Type 1 diabetes, but there now has been some reported success in using this therapy to treat Type 2 diabetes.

With gene therapy, doctors insert lab-designed genes into patients to help treat medical conditions. A research article appearing in the Journal of Clinical Investigation describes researchers using this technique to improve insulin sensitivity in laboratory mice with diabetes.

In the experiment, the mice had been given a high-fat diet to induce the type of insulin resistance that is characteristic of Type 2 diabetes. They then were given an IV infusion of a virus carrying the amino acid peptide urocortin 2. With a single treatment, the mice showed increased levels of the urocortin hormone, indicating improved insulin sensitivity; this result lasted for seven weeks. In addition, when the treatment was given to non-diabetic mice, the researchers discovered that those mice maintained fasting glucose levels that were lower than before the treatment."

From Here
http://www.type2nation.com/treatmen...iabetes-improves-insulin-sensitivity-in-mice/

My point exactly. Another nail in the carb coffin. They used diet to induce diabetes in the mice. Nothing to do with mice having a rogue gene increasing risk. Blunt force trauma aka pate foie gras, Also nothing to do with mice genes at all, simply using a virus as a carrier, which is a different thing.

 

[ickihun]

Would knowing that diabetes has a defined risk from being pased on via genetics that you can do nothing to prevent act as a contraceptive? Would you choose not to have kids knowing that you may be passing on a bad gene that may (possibly) end up with them being diabetic? Would you go so far as to terminate a pregnancy because of this risk?

I ask these as rhetorical questions, and do not expect a reply, but these are things that we in society need to consider if a link is proven. It is the same dilemma facing some parents who can pass on a physical disability due to an already identified gene.

Apart from that, what are you otherwise expecting genetics to do? What will that knowledge actually change in your life as a result of knowing? At least with diet I can achieve a better outcome - now, today - and I can help provide information to others to help them too. I am not a gene scientist, so waiting for them to discover the gene is not something i eagerly wait for since any advances in treatment and prevention will be a long way further down the line. It is something that needs to be done, but is of academic interest only to me.

Remember 3,000 genes relating to diabetes.
I'm hoping most are relating to type1? Or is there only 1 gene relating to type1 and 2,999 relating to type2?

 

[Mr_Pot]

Earlier this year I took part in the DARE study which is a research project investigating the inherited and environmental factors that make some people more likely to develop diabetes. The information they provided said "the genes involved in diabetes are poorly understood". So a long way to go to a gene based cure.

 

[Resurgam]

I think that there is a general misunderstanding of genetics, hereditary, even evolution. If there are - for instance, genes for tall and short individuals, to have either would not be a problem unless the food source could only be reached by tall individuals and it was in short supply. In a world where the food was within reach of all, then no problem, if there was a lot of food, and the tall individuals passed it to the short ones, also no problem - but in times of famine, short ones might become rarer.
But if - for instance, there were big flying things added to the mixture, which swooped down and carried away the taller individuals because they were more visible due to the tall genes being associated with flaming golden-red hair, then the survival of short individuals who banded together in small groups and hoisted up one of their number so they could reach the food would improve, then the shorter individuals would thrive and prosper, but so could tall ones with dark hair.
It is not just a simple have or have not situation, the environment and learned behaviour also count quite strongly in the equation.

 

[CherryAA]

All we really want to know is if there been any studies that actually prove what causes diabetes I think not but what we do know is that some people are more predisposed to it than others no matter what they do. There is much more about diabetes not yet discovered If only it was as simple as diet then the world would be cured or prevented from getting it. Until the cause is found we can only wait and carry on with what we do to control ours

As far as I know there isn't However I do have an idea

If I am right then its nothing less than a unified theory of world health .

I am going to write a book - ! - it my theory is right it will make it to the end of the writing process. if not it will sink without trace